Strengthening Global Systems to Prevent and Respond to High Consequence Biological Threats

Strengthening Global Systems to Prevent and Respond to High Consequence Biological Threats is a November 2021 paper published by the Nuclear Threat Initiative summarizing a tabletop exercise conducted at the 2021 Munich Security Conference. It focuses on a hypothetical scenario involving the global public health response to an intentional release of a lab-manipulated strain of monkeypox, later attributed to terrorists.

The project was funded by Open Philanthropy.

Personnel

Authors

The scenario for the exercise was authored by Jaime Yassif, Kevin O'Prey and Christopher Isaac.1)

O'Prey is a Managing Partner at the Palisades Group.

Margaret Hamburg wrote the introduction.

Participants

Name Affiliation
Ernest Moniz Nuclear Threat Initiative
Wolfgang Ischinger Munich Security Conference
Arnaud Bernaert SICPA
Beth Cameron United States National Security Council
Luc Debruyne Coalition for Epidemic Preparedness Innovations (CEPI)
Ruxandra Draghia-Akli Johnson & Johnson; Janssen
Chris Elias Bill & Melinda Gates Foundation
Jeremy Farrar Wellcome Trust
George Gao Chinese Center for Disease Control and Prevention; National Natural Science Foundation of China; Chinese Academy of Sciences; University of Chinese Academy of Sciences
Margaret Hamburg Nuclear Threat Initiative
Angela Kane Paris School of International Affairs; Tsinghua University
Emily Leproust Twist Bioscience
Elisabeth Leiss German Corporation for International Cooperation (GIZ)
Izumi Nakamitsu United Nations Office for Disarmament Affairs
John Nkengasong Africa Centres for Disease Control and Prevention
Sam Nunn Nuclear Threat Initiative
Michael Ryan WHO Health Emergencies Programme
Joy St. John Caribbean Public Health Agency (CARPHA)
Petra Wicklandt Merck
Expert Contributors
Hillary Carter United States Department of Homeland Security
Sarah Carter Science Policy Consulting
Bradley Dickerson Sandia National Laboratories
Diane DiEuliis National Defense University
James Diggans Twist Biosciences
Jessica Dymond Johns Hopkins Applied Physics Laboratory
Dylan George Gingko Bioworks; In-Q-Tel
John Glass J. Craig Venter Institute Synthetic Biology Group
Amanda Glassman Center for Global Development
William Hanage Harvard T.H. Chan School of Public Health
Lawrence Kerr United States Department of Health and Human Services
Jeremy Konyndyk United States Agency for International Development (USAID)
Bob Mikulak United States Department of State
Ryan Morhard Gingko Bioworks
Jennifer Nuzzo Johns Hopkins Bloomberg School of Public Health
Megan Palmer Stanford University
Chris Park United States Department of State
Carolyn Reynolds Pandemic Action Network
Deborah Rosenblum Nuclear Threat Initiative
Jonas Sandbrink Future of Humanity Institute

Associated organizations

The event was jointly held with the Munich Security Conference. Talus Analytics developed the underlying epidemiological model for the exercise. Long Story Short produced the video content.

Several individuals from the Nuclear Threat Initiative are described as helping organize the event and/or report, including Dr. Andrew Hebbeler, Amanda Cogan, Rachel Staley Grant, and Mimi Hall.

1)
Yassif, J., Kevin, P., O'prey, Christopher, R., & Isaac. (2021). Strengthening Global Systems to Prevent and Respond to High-Consequence Biological Threats. Nuclear Threat Initiative. https://www.nti.org/wp-content/uploads/2021/11/NTI_Paper_BIO-TTX_Final.pdf
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