David Boulware

David R. Boulware, MD, MPH is an American infectious diseases researcher based in Minnesota. He is a professor and physician at the University of Minnesota Medical School and faculty member at the University of Minnesota School of Public Health.¹⁾

Boulware served as principal investigator in the first randomized clinical trial testing hydroxychloroquine for the post-exposure prevention of COVID-19, which began on March 17, 2020.²⁾ The study, titled “Post-exposure Prophylaxis or Preemptive Treatment for SARS-Coronavirus-2”, was funded by Jan and David Baszucki, Steve Kirsch, University of Minnesota Foundation, the Alliance of Minnesota Chinese Organizations and Minnesota Chinese Chamber of Commerce.³⁾ Further funding for the Canadian arms of the trial came from:

• Bridge to Health Medical and Dental
• Manitoba Medical Service Foundation
• McGill Interdisciplinary Initiative in Infection and Immunity (MI4)
• McGill University Health Centre (MUHC)
• Northern Alberta Clinical Trials and Research Centre
• Research Institute of St. Joe's Hamilton
• St. Joseph's Hospital Foundation

Collaborators and trial sites included the University of Minnesota, University of Alberta, University of Manitoba and the Research Institute of the McGill University Health Centre.⁴⁾ The hydroxychloroquine for the trial was donated by Rising Pharmaceuticals.⁵⁾

On June 3, 2020, the results of Boulware's trial were published in the New England Journal of Medicine (NEJM), finding that “hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure.”⁶⁾

Boulware's areas of research and clinical trials include cryptococcus, HIV, meningitis, sertraline and tuberculosis.

He has received research funding from:⁷⁾

• Doris Duke Charitable Foundation
• Fogarty International Center (FIC)
• GlaxoSmithKline
• Hennepin Healthcare Research Institute
• Infectious Diseases Institute (IDI)
• Matinas BioPharma
• National Institute of Allergy and Infectious Diseases (NIAID)
• National Institutes of Health (NIH)
• National Institute of Neurological Disorders and Stroke (NINDS)
• University of California San Francisco (UCSF)
• University of Kansas Medical Center
• University of Minnesota Foundation
• University of Virginia

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