Zhengli Shi
History
Education
Shi earned her masters degree from the Wuhan Institute of Virology in 1990. Later, she earned her PhD in France at the Montpellier 2 University while becoming fluent in French.
Career
Director of Wuhan Institute of Virology
Coronavirus Research
2005
In the wake of the 2002-2003 SARS-CoV outbreak, Shi and collegues found that bats are a natural reservoir of SARS-like CoVs.1)
2013
In 2013, researchers at the Wuhan Institute of Virology published a paper saying that Dr. Zhengli Shi and EcoHealth Alliance's Dr. Peter Daszak found CoVs that were 95% identical to human SARS-CoV in Chinese horseshoe bats. Further, these CoVs “were able to use human angiotensin-converting enzyme 2 (ACE2) receptor for docking and entry.”2)
2020
In March 2020, Shi and co-authors published a paper asserting that Remdesivir and chloroquine worked as therapeutics against SARS-CoV-2.3)
External links
1)
october 31, 2005 | Li Wendong et al including Shi Zhengli and Peter Daszak | Science (journal) | Bats Are Natural Reservoirs of SARS-Like Coronaviruses | https://doi.org/10.1126/science.1118391
2)
December, 2013 | Manli Wang and Zhihong Hu | Virol Sin. (journal) | Bats as animal reservoirs for the SARS coronavirus: Hypothesis proved after 10 years of virus hunting | doi: 10.1007/s12250-013-3402-x
3)
Wang, M., Cao, R., Zhang, L., Yang, X., Liu, J., Xu, M., Shi, Z., Hu, Z., Zhong, W., & Xiao, G. (2020). Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Research, 30(3), 269–271. https://doi.org/10.1038/s41422-020-0282-0