This is an old revision of the document!
Spike Protein
What is a spike protein. Function of spike protein. Spike in other coronaviruses. Discuss past implications of spike in pathologies.
SARS-CoV-2 Spike Protein
Mention ACE2 affinity relative to SARS spike protein. Specific characteristics including those which point to lab origin. Specific and detail ACE2 binding information.
Explain spike protein as a target for antibodies and value in vaccine manufacturing.
Proposed Mechanisms of SARS-CoV-2 Spike Protein Pathology
Detail effects of ACE2 down-regulation and subsequent impact on RAAS. Detail role of Angiotensin 2 in inflammation, clotting, angiogenesis, etc.
AGE/RAGE connection with Ang 2 pathology.
Link Dump
Spike protein clotting