Parker Institute for Cancer Immunotherapy

The Parker Institute for Cancer Immunotherapy (PICI) is an American non-profit research collaboration based in San Francisco, California. It was founded by Napster and Facebook co-founder Sean Parker.

History

Founding

In April 2016, Sean Parker announced $250 million in funding to establish the PICI as a consortium to unite leading cancer researchers around the United States.1) The funds initially went to over 300 scientists at 40 laboratories, situated across six institutions: University of Stanford, the University of California San Francisco, University of California Los Angeles, the University of Pennsylvania, MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center.

CRISPR trials

Starting in 2016, the Parker Institute for Cancer Immunotherapy scientists funded a clinical trial to test T-cells engineered using CRISPR gene-editing technology.2) The trial was the first in the United States to test CRISPR-modified cells in humans.3) The trial is led by the University of Pennsylvania and is also conducted at University of California San Francisco and the University of Texas MD Anderson Cancer Center.

The Institute is also collaborating with MD Anderson and Seres Therapeutics to launch a microbiome-cancer immunotherapy clinical trial for advanced melanoma patients.4)

Organization

Personnel

Name Position Affiliation

Network

Partners

1)
Cha, A. E. (2016, April 13). $250 million, 300 scientists and 40 labs: Sean Parker’s revolutionary project to “solve” cancer. Washington Post. https://archive.ph/n8oUT
2)
Lorenzetti, L. (2016, June 21). Sean Parker Is Funding the First Human Trials of a Revolutionary Cancer Treatment. Fortune. https://web.archive.org/web/20221204063056/https://fortune.com/2016/06/21/sean-parker-first-crispr-trial/
3)
Regalado, A. (2016, June 20). Money Behind First CRISPR Test? It’s from Internet Billionaire Sean Parker. MIT Technology Review. https://web.archive.org/web/20221204063109/https://www.technologyreview.com/2016/06/20/245678/money-behind-first-crispr-test-its-from-internet-billionaire-sean-parker/
4)
Kaiserr, J. (2017, November 2). Your gut bacteria could determine how you respond to cutting-edge cancer drugs. Science. https://web.archive.org/web/20221204063738/https://www.science.org/content/article/your-gut-bacteria-could-determine-how-you-respond-cutting-edge-cancer-drugs
5)
Research Institutions. Parker Institute for Cancer Immunotherapy. Retrieved December 4, 2022, from https://archive.ph/6NnPl
6)
Partners. Parker Institute for Cancer Immunotherapy. Retrieved December 4, 2022, from https://web.archive.org/web/20221204073814/https://www.parkerici.org/network/directory/partners/
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