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Hélène Decaluwe
Education
Decaluwe graduated from the Faculty of Medicine at McGill University and completed her residency in pediatrics at the CHU Sainte-Justine in partnership with the University of Montreal.
She then completed her training in pediatric clinical immunology at the Necker Enfants-Malades Hospital in Paris, France with Professor Alain Fischer. Her research training includes a Master and a PhD degree in immunology at Pierre and Marie Curie University carried out in the laboratories of Professor Jean-Laurent Casanova and Professor James Di Santo respectively.
Career and Affiliations
CHU Sainte-Justine
Associate Professor in the Immunology and Rheumatology Division of the CHU Sainte-Justine since 2010 and Clinician Scientist and outgoing Deputy Head of the Immune Diseases and Cancer Research Axis at the CHU Sainte-Justine Research Center.
National Advisory Committee on Immunization
Decaluwe is a member of the National Advisory Committee on Immunization (NACI).1)
Research
Decaluwe has dedicated her career to resolving the mechanisms of T cell differentiation in health, infection and primary immune deficiencies. The primary focus of her research is to better understand the role of cytokines in the differentiation of T cells in health and disease, and to develop novel immunotherapeutic approaches that target cytokine-dependent pathways and inhibitory receptors expressed on T cells, to cure chronic viral infections and cancer.
Funding
She is funded by the Fonds de Recherche du Québec en Santé (FRQS), Canadian Institutes of Health Research, National Institutes of Health, Canadian Cancer Society, Cole Foundation, Charles Bruneau Foundation, Leukemia and Lymphoma Society of Canada, and the COVID-19 Immunity Task Force.
COVID-19
RECOVER
Decaluwe is a co-investigator in the REinfection in COVid-19 Estimation of Risk (RECOVER study), alongside Caroline Quach-Thanh. The study is funded by the Canadian Institutes of Health Research, and the Public Health Agency of Canada through the COVID-19 Immunity Task Force.2)
PITCH
Decaluwe is a co-Principal Investigator in the Persistence of T cell Immunity in Children with SARS-CoV-2 and Household contacts (PITCH Study), funded by the Children's Hospital Academic Medical Organization (CHAMO) innovation fund and the PSI Foundation.3)
1)
Public Health Agency of Canada. (2022, February 25). National Advisory Committee on Immunization (NACI): Membership and representation. Government of Canada. https://web.archive.org/web/20220318105951/https://www.canada.ca/en/public-health/services/immunization/national-advisory-committee-on-immunization-naci/naci-membership-representation.html#fn1-rf
2)
Racine, É., Boivin, G., Longtin, Y., McCormack, D., Decaluwe, H., Savard, P., Cheng, M. P., Hamelin, M.-È., Tadount, F., Adams, K., Bourdin, B., Nantel, S., Gilca, V., Corbeil, J., De Serres, G., & Quach, C. (2022). The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers. medRxiv, Preprint. https://doi.org/10.1101/2022.02.10.22269967
3)
Decaluwe, H. Post-doctoral fellowship in COVID-19 Immunology CHU Sainte-Justine Research Center Title: T cell responses in COVID-19 patients following infection and/or vaccination. CHU Sainte-Justine Research Center. Retrieved May 22, 2022, from https://web.archive.org/web/20220522125556/https://research.chusj.org/RECHERCHE/files/71/717465d5-a2e8-42ac-8abf-509cb48c95b5.pdf