Hélène Decaluwe

Dr. Hélène Decaluwe is a Canadian immunologist based in Montreal, Quebec.

Decaluwe graduated from the Faculty of Medicine at McGill University and completed her residency in pediatrics at the CHU Sainte-Justine in partnership with the University of Montreal.

She then completed her training in pediatric clinical immunology at the Necker Enfants-Malades Hospital in Paris, France with Professor Alain Fischer. Her research training includes a Master and a PhD degree in immunology at Pierre and Marie Curie University carried out in the laboratories of Professor Jean-Laurent Casanova and Professor James Di Santo respectively.

Associate Professor in the Immunology and Rheumatology Division of the CHU Sainte-Justine since 2010 and Clinician Scientist and outgoing Deputy Head of the Immune Diseases and Cancer Research Axis at the CHU Sainte-Justine Research Center.

Decaluwe is a member of the National Advisory Committee on Immunization (NACI).¹⁾

As a clinical researcher supported by the Fonds de Recherche du Québec en Santé (FRQS), she has dedicated her career to resolving the mechanisms of T cell differentiation in health, infection and primary immune deficiencies. The primary focus of her research is to better understand the role of cytokines in the differentiation of T cells in health and disease, and to develop novel immunotherapeutic approaches that target cytokine-dependent pathways and inhibitory receptors expressed on T cells, to cure chronic viral infections and cancer.