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sars-cov-2:origins:zoonotic_origins_hypothesis [2022/07/31 15:43]
mathew
sars-cov-2:origins:zoonotic_origins_hypothesis [2022/07/31 18:05] (current)
mathew
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 ====== Zoonotic Origins Hypothesis ====== ====== Zoonotic Origins Hypothesis ======
-Since the start of the pandemic, authorities have primarily promoted a [[SARS-CoV-2:origins]] theory of zoonotic transfer from an animal host to humans. A group of researchers going by the name [[:D.R.A.S.T.I.C.]] has sought to counter what they consider a propaganda campaign by government, military, and industry to make it appear that the origins of SARS-CoV-2 are zoonotic.+Since the start of the pandemic, authorities have primarily promoted a [[SARS-CoV-2:origins]] theory of [[:zoonosis|zoonotic]] transfer from an animal host to humans. A group of researchers going by the name [[:D.R.A.S.T.I.C.]] has sought to counter what they consider a propaganda campaign by government, military, and industry to make it appear that the origins of SARS-CoV-2 are zoonotic.
  
 ===== Huanan Seafood Wholesale Market in Wuhan, China ===== ===== Huanan Seafood Wholesale Market in Wuhan, China =====
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 ===== Bat Coronaviruses ===== ===== Bat Coronaviruses =====
-SARS-CoV-2 is most highly similar to coronaviruses that have been found in bats.+With the notable except of the spike protein, the genetric sequence that makes up SARS-CoV-2 is most highly similar to those of coronaviruses that have been found in bats. 
 + 
 +In 2015, scientists including [[:Ralph Baric]] and [[:Shi Zhengli]] published a paper noting the existence of SARS-like coronaviruses showing "potential for human emergence".((November 9, 2015 | Vineet Menachery et al | Nature Medicine | A SARS-like cluster of circulating bat coronaviruses  
 +shows potential for human emergence | [[https://www.nature.com/articles/nm.3985/|doi.org/10.1038/nm.3985))
  
 The [[:RaTG13]] [[:betacoronavirus]] is the most highly similar coronavirus to SARS-CoV-2, sharing 98.7% identical mitochondrial [[:rRNA]], but was supposedly generated from a bat fecal swab, which strikes some scientists as unlikely since metagenomic analysis shows a small 10.3% bacterial rRNA in the dataset.((November 22, 2021 | Steven E Massey | preprint | [[https://arxiv.org/abs/2111.09469|arXiv:2111.09469]])) The [[:RaTG13]] [[:betacoronavirus]] is the most highly similar coronavirus to SARS-CoV-2, sharing 98.7% identical mitochondrial [[:rRNA]], but was supposedly generated from a bat fecal swab, which strikes some scientists as unlikely since metagenomic analysis shows a small 10.3% bacterial rRNA in the dataset.((November 22, 2021 | Steven E Massey | preprint | [[https://arxiv.org/abs/2111.09469|arXiv:2111.09469]]))
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