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sars-cov-2:origins:genetic_engineering_hypothesis [2022/04/15 09:46]
mathew | sars-cov-2:origins:genetic_engineering_hypothesis [2022/11/13 02:50] (current)
mathew |
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| ===== Genetic Evidence of Engineering ===== | ===== Genetic Evidence of Engineering ===== |
| Early during the pandemic, scientists compared the SARS-CoV-2 genome to CoVs native to several species. SARS-CoV-2 was most similar per [[:nucleotide]] to bat CoVs, but more similar in [[:codon]] bias to snakes. Simiarity to all species largely disappeared in the [[:spike protein]] portion of the genome, which is suggestive of a radical divergence from nature.((January 22, 2020 | Wei Ji et al | Journal of Medical Virology | Cross-species transmission of the newly identified coronavirus 2019-nCoV | [[https://onlinelibrary.wiley.com/doi/10.1002/jmv.25682|https://doi.org/10.1002/jmv.25682]])) | Early during the pandemic, scientists compared the SARS-CoV-2 genome to CoVs native to several species. SARS-CoV-2 was most similar per [[:nucleotide]] to bat CoVs, but more similar in [[:codon]] bias to snakes. Simiarity to CoVs from all observed species largely disappeared in the [[:spike protein]] portion of the genome, which is suggestive of a radical divergence from nature.((January 22, 2020 | Wei Ji et al | Journal of Medical Virology | Cross-species transmission of the newly identified coronavirus 2019-nCoV | [[https://onlinelibrary.wiley.com/doi/10.1002/jmv.25682|https://doi.org/10.1002/jmv.25682]])) Karl and Dan Sirotkin published a paper critiquing [[:gain-of-function]] research and exploring molecular and genetic evidence pointing toward likely lab origins.((October, 2020 | Karl Sirotkin and Dan Sirotkin | Bioessays (journal) | Might SARS‐CoV‐2 Have Arisen via Serial Passage through an Animal Host or Cell Culture? | [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7435492/|doi: 10.1002/bies.202000091]])) |
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| | A group of scientists tried and failed to recreate the furin cleavage site through infection.((July 20, 2022 | Adeno News | [[http://adeno-news.com/2022/07/20/scientists-struggles-to-recreate-the-sars-cov-2-furin-cleavage-site-through-infection/|Scientists struggles to recreate the SARS-CoV-2 furin cleavage site through infection]])) |
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| | ==== Statistical Evidence ==== |
| | * Preprint: Bruttel, Washburne, and VanDongen |
| | https://www.biorxiv.org/content/10.1101/2022.10.18.512756v1.full |
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| ===== Moderna Links ===== | ===== Moderna Links ===== |
| ===== Biological Attack (Sub)Hypothesis ===== | ===== Biological Attack (Sub)Hypothesis ===== |
| A long and detailed article published in [[State of the Nation]] lays out a case that [[:COVID-19]] was the result of a biological attack on [[:China]] by the U.S.((March 14, 2020 | [[State of the Nation]] | [[https://stateofthenation.co/?p=9167|COVID-19: A Biological Attack on China by the USA]])) | A long and detailed article published in [[State of the Nation]] lays out a case that [[:COVID-19]] was the result of a biological attack on [[:China]] by the U.S.((March 14, 2020 | [[State of the Nation]] | [[https://stateofthenation.co/?p=9167|COVID-19: A Biological Attack on China by the USA]])) |
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| | ==== Toxins ==== |
| | Research report finding [[:toxin]]-like peptides similar to those in animal [[:venom]] (conotoxins, phospholipsases, phosphodiesterases, zinc metal proteinases, and bradykinins) were found in fecal samples from COVID-19 patients, but not in control patients.((October 14, 2021 | Carlo Brogna et al | F1000 Research (journal) | Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients | [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772524/#|doi: 10.12688/f1000research.54306.2]])) |
