You are here: Welcome » Ivermectin

Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revisionPrevious revision
Next revision		Previous revision
Both sides next revision
ivermectin [2022/10/04 00:34]
pamela [Ivermectin] 		ivermectin [2022/10/13 19:03] (current)
pamela [Mainstream Media Campaign]
Line 1: Line 1:
 ===== Ivermectin ===== ===== Ivermectin =====
  
-**Ivermectin** is an [[:antiparasitic]] agent with antiviral properties that is approved by the FDA and WHO for a myriad of treatments. It is listed as an essential medicine by the WHO. +**Ivermectin** is an [[antiparasitic]] agent with [[antiviral]] properties that is approved by the FDA and the [[World Health Organization]] for a myriad of treatments. It is listed as an essential medicine by the WHO. 
  
 The bacterium Streptomyces avermictilis was first discovered in the soils of Japan in the 1960s by Satoshi Ōmura while searching for new antibacterial agents. After some altering to improve its safety the resulting compound was dubbed ivermectin. It was first approved for use in animals in 1981 and later in 1987 for the treatment of river blindness in sub-Saharan Africa. Since then Merck Laboratories have donated billions of doses globally for the treatment of onchocerciasis and lymphatic filariasis and other worm-caused diseases. William C.  The bacterium Streptomyces avermictilis was first discovered in the soils of Japan in the 1960s by Satoshi Ōmura while searching for new antibacterial agents. After some altering to improve its safety the resulting compound was dubbed ivermectin. It was first approved for use in animals in 1981 and later in 1987 for the treatment of river blindness in sub-Saharan Africa. Since then Merck Laboratories have donated billions of doses globally for the treatment of onchocerciasis and lymphatic filariasis and other worm-caused diseases. William C. 
Line 7: Line 7:
 A paper titled 'Ivermectin, ‘Wonder drug’ from Japan: the human use perspective' by Crump & Omura.(([[https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3043740/ | 'Ivermectin, ‘Wonder drug’ from Japan: the human use perspective']])) A paper titled 'Ivermectin, ‘Wonder drug’ from Japan: the human use perspective' by Crump & Omura.(([[https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3043740/ | 'Ivermectin, ‘Wonder drug’ from Japan: the human use perspective']]))
  
-==== 2010 Ivermectin in Human Disease ====+===== Ivermectin's Discovery and Recognition ===== 
 + 
 +==== 2015 Nobel Prize ==== 
 + 
 +In 2015 [[William Campbell]] and [[Satoshi Ömura]] were awarded a [[Nobel Prize]] for the drug.((https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539925/))((https://www.isglobal.org/en/healthisglobal/-/custom-blog-portlet/ivermectina-del-suelo-a-las-lombrices-y-mas-alla/3098670/0)) 
 + 
 +===== Antiparasitic Usage ===== 
 + 
 +==== Malaria Treatment ==== 
 +Research indicates that mass administration of ivermectin lowers [[malaria]] rates with essentially no side effects.((March 13, 2019 | Brian D Foy et al | [[The Lancet]] | Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial | [[https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32321-3/fulltext|https://doi.org/10.1016/S0140-6736(18)32321-3]])) 
 {{ ::chris_whitty_2010_ivermectin_study.png?600|}} {{ ::chris_whitty_2010_ivermectin_study.png?600|}}
 Effect of Ivermectin on Anopheles gambiae Mosquitoes Fed on Humans: The Potential of Oral Insecticides in Malaria Control Effect of Ivermectin on Anopheles gambiae Mosquitoes Fed on Humans: The Potential of Oral Insecticides in Malaria Control
Line 14: Line 24:
 Published: 01 July 2010 Published: 01 July 2010
  
-Quote [[:Chris Whitty]]: "Ivermectin has a wide antiparasitic activity with long veterinary use [4]. When ivermectin's activity against Onchocerca volvulus was discovered, it was licensed for human use and was used in mass drug administration programs to control river blindness; it was administered to >80 million adults and children. The drug has proven to be safe. Doses up to 10 times the approved limit are well tolerated by healthy volunteers [5]. Adverse reactions are few and usually mild [6, 7]." ((https://web.archive.org/web/20220127114341/https://academic.oup.com/jid/article/202/1/113/888773?login=false)) +==== Veterinary Usage ==== 
- +Quote [[:Chris Whitty]]: "Ivermectin has a wide antiparasitic activity with long veterinary use [4]. When ivermectin's activity against [[Onchocerca volvulus]] was discovered, it was licensed for human use and was used in mass drug administration programs to control river blindness; it was administered to >80 million adults and children. The drug has proven to be safe. Doses up to 10 times the approved limit are well tolerated by healthy volunteers [5]. Adverse reactions are few and usually mild [6, 7]." ((https://web.archive.org/web/20220127114341/https://academic.oup.com/jid/article/202/1/113/888773?login=false))
- +
-==== 2015 Nobel Prize ==== +
- +
-In 2015 [[William Campbell]] and [[Satoshi Ömura]] were awarded a [[Nobel Prize]] for the drug.((https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539925/))((https://www.isglobal.org/en/healthisglobal/-/custom-blog-portlet/ivermectina-del-suelo-a-las-lombrices-y-mas-alla/3098670/0))+
  
  
 +===== Controversy During the COVID-19 Pandemic =====
 +During the [[COVID-19 pandemic]], the use of ivermectin to prevent or treat [[COVID-19]] became highly controversial.
  
 ==== The Global Disinformation Campaign Against Ivermectin in COVID-19 (Part I) ====  ==== The Global Disinformation Campaign Against Ivermectin in COVID-19 (Part I) ==== 
Line 34: Line 42:
 ==== Mainstream Media Campaign ==== ==== Mainstream Media Campaign ====
  
-Touted in the mainstream press as "horse dewormer," ivermectin is that and more. It is important to take into consideration that any acceptance of ivermectin as a viable treatment for covid-19 puts at risk the vaccination campaign under Emergency Use Authorization and all policies associated with it.+Touted in the mainstream press as "horse dewormer," ivermectin is that and more. It is important to take into consideration that any acceptance of ivermectin as a viable treatment for covid-19 puts at risk the vaccination campaign under [[:Emergency Use Authorization]] and all policies associated with it.
  
 August 26 2021, the CDC issued a ((https://emergency.cdc.gov/han/2021/pdf/CDC_HAN_449.pdf | Health Advisory)) titled "Rapid Increase in Ivermectin Prescriptions and Reports of Severe Illness Associated with Use of Products Containing Ivermectin to Prevent or Treat COVID-19". It later emerged that this was based on scant evidence; just three cases of alleged ivermectin side effects, two involving animal formulations. No patient died; one appeared to have been hospitalized, and one declined any medical help.  August 26 2021, the CDC issued a ((https://emergency.cdc.gov/han/2021/pdf/CDC_HAN_449.pdf | Health Advisory)) titled "Rapid Increase in Ivermectin Prescriptions and Reports of Severe Illness Associated with Use of Products Containing Ivermectin to Prevent or Treat COVID-19". It later emerged that this was based on scant evidence; just three cases of alleged ivermectin side effects, two involving animal formulations. No patient died; one appeared to have been hospitalized, and one declined any medical help. 
Back to top