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discovery_of_medical_countermeasures_against_novel_entities [2023/03/13 04:56]
liam [COVID-19] 		discovery_of_medical_countermeasures_against_novel_entities [2025/07/07 05:32] (current)
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 In early 2020, [[Michael Callahan]] alerted his colleague [[Robert Malone]], then working as chief medical officer at [[pharmaceutical_companies:Alchem Laboratories]], of the emerging [[SARS-CoV-2]] outbreak in [[china:Wuhan]], [[China]]. Malone was also working on the DOMANE project, which identified several drugs approved by the [[Food and Drug Administration]] (FDA) that may work as potential treatments against [[COVID-19]], the disease thought to result from infection with the virus.((Borrell, B. (2020). //New York clinical trial quietly tests heartburn remedy against coronavirus.// Science. https://doi.org/10.1126/science.abc4739)) In early 2020, [[Michael Callahan]] alerted his colleague [[Robert Malone]], then working as chief medical officer at [[pharmaceutical_companies:Alchem Laboratories]], of the emerging [[SARS-CoV-2]] outbreak in [[china:Wuhan]], [[China]]. Malone was also working on the DOMANE project, which identified several drugs approved by the [[Food and Drug Administration]] (FDA) that may work as potential treatments against [[COVID-19]], the disease thought to result from infection with the virus.((Borrell, B. (2020). //New York clinical trial quietly tests heartburn remedy against coronavirus.// Science. https://doi.org/10.1126/science.abc4739))
  
-One of the first drugs identified was [[Remdesivir]], an experimental product developed by [[pharmaceutical_companies:Gilead Sciences]] for use against [[Ebola]].((Gardner, D. (2021, February 4). //DTRA’s Therapeutic Arm Latches on to FDA-approved and Affordable Drugs for COVID-19 Relief.// Defense Visual Information Distribution Service. http://archive.today/2023.02.26-224227/https://www.dvidshub.net/news/388359/dtras-therapeutic-arm-latches-fda-approved-and-affordable-drugs-covid-19-relief))+One of the first drugs identified was [[remdesivir]], an experimental product developed by [[pharmaceutical_companies:Gilead Sciences]] for use against [[Ebola]].((Gardner, D. (2021, February 4). //DTRA’s Therapeutic Arm Latches on to FDA-approved and Affordable Drugs for COVID-19 Relief.// Defense Visual Information Distribution Service. http://archive.today/2023.02.26-224227/https://www.dvidshub.net/news/388359/dtras-therapeutic-arm-latches-fda-approved-and-affordable-drugs-covid-19-relief))
  
 Another candidate for repurposing was [[famotidine]], an anti-heartburn drug marketed in the [[United States]] by [[pharmaceutical_companies:Johnson & Johnson]] as Pepcid.((Halford, B. (2020, June 15). //Can Pepcid treat COVID-19?// Chemical & Engineering News. https://web.archive.org/web/20200711060533/https://cen.acs.org/pharmaceuticals/Pepcid-treat-COVID-19/98/i25)) ((Shoaibi, A., Fortin, S., Weinstein, R., Berlin, J. A., & Ryan, P. (2020). //Comparative Effectiveness of Famotidine in Hospitalized COVID-19 Patients.// medRxiv. https://doi.org/10.1101/2020.09.23.20199463)) On April 14, the [[Biomedical Advanced Research and Development Authority]] (BARDA) awarded Alchem a $20.7 million contract the conduct a clinical trial on the drug. Another candidate for repurposing was [[famotidine]], an anti-heartburn drug marketed in the [[United States]] by [[pharmaceutical_companies:Johnson & Johnson]] as Pepcid.((Halford, B. (2020, June 15). //Can Pepcid treat COVID-19?// Chemical & Engineering News. https://web.archive.org/web/20200711060533/https://cen.acs.org/pharmaceuticals/Pepcid-treat-COVID-19/98/i25)) ((Shoaibi, A., Fortin, S., Weinstein, R., Berlin, J. A., & Ryan, P. (2020). //Comparative Effectiveness of Famotidine in Hospitalized COVID-19 Patients.// medRxiv. https://doi.org/10.1101/2020.09.23.20199463)) On April 14, the [[Biomedical Advanced Research and Development Authority]] (BARDA) awarded Alchem a $20.7 million contract the conduct a clinical trial on the drug.
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 DTRA also partnered with [[Quantum Leap Healthcare]] and [[Leidos]] to conduct clinical trials on various combinations of the repurposed drugs. DTRA also partnered with [[Quantum Leap Healthcare]] and [[Leidos]] to conduct clinical trials on various combinations of the repurposed drugs.
 +
 +=== Treatment of Donald Trump ===
 +
 +According to //[[Vanity Fair]]//, the DOMANE team made contact with White House physician [[Sean Conley]] in regards to the protocol used to treat President [[Donald Trump]] when he was diagnosed with [[COVID-19]].((Nast, C. (2020, October 5). //Quack Cures Lose Their Appeal Now That Trump Himself Is Sick With COVID-19.// Vanity Fair. http://archive.today/2023.03.28-002251/https://www.vanityfair.com/news/2020/10/quack-cures-lose-their-appeal-now-that-trump-himself-is-sick-with-covid-19))
  
 DOMANE was featured in the January 2021 issue of //[[JSTO in the News]],// in which the program was described as using the [[COVID-19 pandemic]] as a "proof-of-concept" for future use in [[biodefense]].((Research and Development Directorate. (2021). //A New DOMANE: Biodefense in a Pandemic Era.// JSTO in the News, 11(1). https://www.dvidshub.net/publication/issues/57177)) It describes the use of "virtual clinical trials" involving [[wearable technology|wearables]], [[telehealth]], "e-consent", and electronic storage of patient information. DOMANE was featured in the January 2021 issue of //[[JSTO in the News]],// in which the program was described as using the [[COVID-19 pandemic]] as a "proof-of-concept" for future use in [[biodefense]].((Research and Development Directorate. (2021). //A New DOMANE: Biodefense in a Pandemic Era.// JSTO in the News, 11(1). https://www.dvidshub.net/publication/issues/57177)) It describes the use of "virtual clinical trials" involving [[wearable technology|wearables]], [[telehealth]], "e-consent", and electronic storage of patient information.
 +
 +=== Robert Malone Denial of DOMANE Influence ===
 +Substack -  Puppet Masters of the Pandemic. Part 1: What Did The CIA Do in Wuhan?"
 +Part 1 of an interview with the New American Magazine
 +Robert W Malone MD, MS - Aug 3, 2023
 +
 +By the way, the whole storyline that I was in charge of programs at DTRA is laughable. I was a small subcontractor with a DoD secret clearance. There's no way that a subcontractor would be given a programmatic authority over major biodefense programs such as DOMANE. So that's a whole false storyline that's been developed and repeatedly amplified by some of my detractors.
 +
 +And yes, DOMANE did take credit for the development of Remdesivir because of what DTRA had done during the Ebola outbreak, working together with Michael Callahan. ((https://rwmalonemd.substack.com/p/puppet-masters-of-the-pandemic-part))
  
 ===== External links ===== ===== External links =====
  
   * [[https://sites.google.com/housatonicits.com/home0005/research/domane|Housatonic]]   * [[https://sites.google.com/housatonicits.com/home0005/research/domane|Housatonic]]
 +  * [[https://www.whiteroseintelligence.com/discovery-of-medical-countermeasures-against-novel-entities/|White Rose Wiki]]
   * [[https://en.wikipedia.org/wiki/Defense_Threat_Reduction_Agency|Wikipedia - redirects to Defense Threat Reduction Agency]]   * [[https://en.wikipedia.org/wiki/Defense_Threat_Reduction_Agency|Wikipedia - redirects to Defense Threat Reduction Agency]]
   * [[https://wikispooks.com/wiki/Defense_Threat_Reduction_Agency|Wikispooks (Defense Threat Reduction Agency)]]   * [[https://wikispooks.com/wiki/Defense_Threat_Reduction_Agency|Wikispooks (Defense Threat Reduction Agency)]]
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