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covid-19:treatments:drug_therapies [2021/12/26 12:49]
mathew created
covid-19:treatments:drug_therapies [2022/04/27 15:13] (current)
mathew
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-====== Drug Therapies Researched or Applied During to COVID-19 ======+====== Drug Therapies Researched or Applied to Treat COVID-19 ====== 
 +From early on during the [[:COVID-19 pandemic]], many potential drug therapies became and remain controversial. The various medications in this article may include both effective and ineffective treatments of the [[:SARS-CoV-2]] virus and the resulting [[:COVID-19]] disease state. The primary purpose is to categorize and summarize those treatments here. 
 + 
 +===== How to Procure SARS-CoV-2/COVID-19 Prophylaxis and Treatments ===== 
 +See [[COVID-19:How to Procure Medicine for COVID-19]] 
 + 
 +===== Research Summaries ===== 
 +Hundreds of studies on dozens of drugs used during the COVID-19 pandemic are documented and summaried at [[https://c19early.com/|www.c19study.com]]. 
 + 
 +====Antiseptic Mouth/Nose Wash ==== 
 +  * [[COVID-19:treatments:Povidone-Iodine]] 
 +  * [[COVID-19:treatments:Chlorhexidine]] 
 +  * [[COVID-19:treatments:Cetylpyridinium Chloride]] 
 +  * [[COVID-19:treatments:Chlorhexidine Gluconate]] 
 +  * [[COVID-19:treatments:Iota-Carrageenan]] 
 + 
 +===== Antidepressants ===== 
 +While [[:antidepressants]] may not seem like the most important class of repurposed drugs, COVID-19 is a unique disease, and it may not always be clear what biochemical influences might help some of those affected fight off the disease. 
 +  * [[COVID-19:treatments:drug_therapies:fluvoxamine]]
  
 ===== Antivirals ===== ===== Antivirals =====
 +An [[:antiviral]] agent is any agent that works as an antiviral, and may or may not otherwise be ordinarily recognized as a [[:drug]] or have other medical uses.
 +  * [[COVID-19:treatments:drug_therapies:amodiaquine]]
   * [[COVID-19:treatments:drug_therapies:chloroquine]]   * [[COVID-19:treatments:drug_therapies:chloroquine]]
 +  * [[COVID-19:treatments:drug_therapies:curcumin]]
   * [[COVID-19:treatments:drug_therapies:hydroxychloroquine]]   * [[COVID-19:treatments:drug_therapies:hydroxychloroquine]]
 +  * [[COVID-19:treatments:drug_therapies:favipiravir]]
   * [[COVID-19:treatments:drug_therapies:ivermectin]]   * [[COVID-19:treatments:drug_therapies:ivermectin]]
 +  * [[COVID-19:treatments:drug_therapies:lithium]]
 +  * [[COVID-19:treatments:drug_therapies:molnupiravir]]
 +  * [[COVID-19:treatments:drug_therapies:niclosamide]]
 +  * [[COVID-19:treatments:drug_therapies:nitazoxanide]]
 +  * [[COVID-19:treatments:drug_therapies:PAXLOVID™]]]
 +  * [[COVID-19:treatments:drug_therapies:quercetin]]
   * [[COVID-19:treatments:drug_therapies:remdesivir]]   * [[COVID-19:treatments:drug_therapies:remdesivir]]
 +
 +See also [[COVID-19:treatments:drug_therapies:zinc ionophores]]
 +
 +=====Anti-Androgen Therapy ======
 +  * [[COVID-19:treatments:Spironolactone]]
 +  * [[COVID-19:treatments:Dutasteride]]
 +  * [[COVID-19:treatments:Finasteride]]
 +  * [[COVID-19:treatments:Proxalutamide]]
 +
 +===== Blood Thinners/Anticoagulants =====
 +Since clotting is among the most damaging symptoms of COVID-19, numerous [[:anticoagulants]] have been used by some doctors.
 +
 +===== Fusion Inhibitor Peptides =====
 +
 +==== Enfuvirtide ====
 +An in silico study showed that enfuvirtide can act as a potent [[:SARS-CoV-2]] fusion inhibitor.((September 11, 2020 | Khadijeh Ahmadi et al | Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor: an in silico drug repurposing study | [[https://www.tandfonline.com/doi/full/10.1080/07391102.2021.1871958|https://doi.org/10.1080/07391102.2021.1871958]]))
 +
 +=====Immune Modulators =====
 +  * [[COVID-19:treatments:Dexamethasone]]
 +  * [[COVID-19:treatments:Budesonide (inhaled)]]
 +  * [[COVID-19:treatments:Azithromycin]]
 +  * [[COVID-19:treatments:Interferons]]
 +  * [[COVID-19:treatments:Monoclonal Antibodies]]
 +
 +===== Oxygen =====
 +
 +==== Ventilators ====
 +
 +===== Steroids =====
 +
 +==== Corticosteroids ====
 +
 +====Other Mechanisms of Action ====
 +  * [[COVID-19:treatments:Melatonin]]
 +  * [[COVID-19:treatments:Colchicine]]
 +  * [[COVID-19:treatments:Statins]]
 +  * [[COVID-19:treatments:Aspirin]]
 +  * [[COVID-19:treatments:Famotidine]]
 +
 +==== Public Health Measures ====
 +See [[List of SARS-CoV-2 pandemic public health measures]]
 +
 +
 +==== Vaccines ====
 +Many [[COVID-19 vaccines]] have been deployed with others in the development pipeline.
 +
 +
 +==== Vitamins, Minerals, and Nutraceuticals ====
 +Many vitamins, minerals, and nutraceutical supplements have been proposed, tested, or used in the treatment of SARS-CoV-2 and COVID-19.
 +
 +   * [[Vitamin C]]
 +   * [[Vitamin D3]]
 +   * [[Zinc]]
 +   * [[Quercetin]]
 +   * [[NAC]]
 +   * [[Nigella Sativa]]
 +   * [[Curcumin]]
 +   * [[Probiotics]]
 +   * [[Vitamin A]]
 +   * [[Epigallocatechin-gallate (EGCG)]]
 +   * [[Lactoferrin]]
 +
 +==== Multidrug Treatment Protocols ====
 +Many medical doctors have shared the results of multidrug treatment protocols that they have used with patients in their practice. 
 +
 +^ Protocol Name ^ # of patients treated ^ # of patients hospitalized ^ # of patients died ^ Case Fatality Rate ^
 +| Dr. Syed Haider IVM + FLV((https://drsyedhaider.com/covid-19/my-experience-flccc-treatment-and-prevention-protocols)) |  4,000+  |  5  |  0  |  0  |
 +| Zelenko High Risk Patient Protocol ((https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587171/))|  141  |  4  |  1    0.7%  |
 +| Tyson Farid mild|   7,000    2  |  0  |  0  |
 +| Tyson Farid moderate((https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xx))|   413    7  |  3  |  0.7%  | 
 +| Italy Protocol |  66,000  |  ?  |  4  |  0.00606%  |
 +| Chetty 8th Day Therapy ((https://www.deccanchronicle.com/lifestyle/health-and-wellbeing/310521/is-covid-19-treatment-based-on-trial-and-error.html)) ((https://www.youtube.com/watch?v=OciYTW_BIEs))|  4,000  |
 +| Demello ((https://odysee.com/@DrMobeenSyed:1/dr.-darrell-demello-discusses-covid-3:1))|   10,000+     ??     ??     ??   |  
 +
 +Dr. Peter McCullough has also developed early outpatient treatment protocols, publishing his findings at the end of 2020 and beginning of 2021:
 +https://pubmed.ncbi.nlm.nih.gov/33387997/
 +https://pubmed.ncbi.nlm.nih.gov/32771461/
 +
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