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covid-19:treatments:drug_therapies:remdesivir [2022/02/16 15:06]
pamela 		covid-19:treatments:drug_therapies:remdesivir [2022/02/16 16:17] (current)
leonardo [Wuhan Gang]
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 Today, the U.S. Food and Drug Administration took two actions to expand the use of the **antiviral drug Veklury (remdesivir)** to certain non-hospitalized adults and pediatric patients for the treatment of mild-to-moderate COVID-19 disease. This provides another treatment option to reduce the risk of hospitalization in high-risk patients. Previously, the use of Veklury was limited to patients requiring hospitalization. Today, the U.S. Food and Drug Administration took two actions to expand the use of the **antiviral drug Veklury (remdesivir)** to certain non-hospitalized adults and pediatric patients for the treatment of mild-to-moderate COVID-19 disease. This provides another treatment option to reduce the risk of hospitalization in high-risk patients. Previously, the use of Veklury was limited to patients requiring hospitalization.
  
-“On the heels of the FDA’s recent authorization of two oral antiviral drugs, today’s actions bolster the arsenal of therapeutics to treat COVID-19 and respond to the surge of the omicron variant,” said Patrizia Cavazzoni, M.D., director of the FDA’s Center for Drug Evaluation and Research. “Today’s actions provide adults and pediatric patients, with mild-to-moderate COVID-19 who are at high risk of severe COVID-19, with a treatment option they could receive outside of a traditional inpatient hospital setting, including at skilled nursing facilities, home healthcare settings and outpatient facilities such as infusion centers.” ((https://web.archive.org/web/20220215224728/https://www.fda.gov/news-events/press-announcements/fda-takes-actions-expand-use-treatment-outpatients-mild-moderate-covid-19))+“On the heels of the FDA’s recent authorization of two oral antiviral drugs, today’s actions bolster the arsenal of therapeutics to treat COVID-19 and respond to the surge of the omicron variant,” said [[Patrizia Cavazzoni]], M.D., director of the FDA’s Center for Drug Evaluation and Research. “Today’s actions provide adults and pediatric patients, with mild-to-moderate COVID-19 who are at high risk of severe COVID-19, with a treatment option they could receive outside of a traditional inpatient hospital setting, including at skilled nursing facilities, home healthcare settings and outpatient facilities such as infusion centers.” ((https://web.archive.org/web/20220215224728/https://www.fda.gov/news-events/press-announcements/fda-takes-actions-expand-use-treatment-outpatients-mild-moderate-covid-19))
  
 see also FORBES - The Strange Story Of Remdesivir, A Covid Drug That Doesn’t Work((https://www.forbes.com/sites/jvchamary/2021/01/31/remdesivir-covid-coronavirus/?sh=5cb83be766c2)) see also FORBES - The Strange Story Of Remdesivir, A Covid Drug That Doesn’t Work((https://www.forbes.com/sites/jvchamary/2021/01/31/remdesivir-covid-coronavirus/?sh=5cb83be766c2))
  
 ==== Wuhan Gang ==== ==== Wuhan Gang ====
-Donald Trump was treated with remdesivir in the way that reason dictates: as soon as possible. [[Peter Hotez]] commented, matter-of-factly-+Donald Trump was treated with remdesivir in the way that reason dictates: as soon as possible. [[:Peter Hotez]] commented, matter-of-factly-
  
 Thread on POTUS therapies; Being asked about mab cocktail from Regeneron and remdesivir and what it means?  Thread on POTUS therapies; Being asked about mab cocktail from Regeneron and remdesivir and what it means? 
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 And yet almost everyone else got the drug when it was already too late for it to help. And yet almost everyone else got the drug when it was already too late for it to help.
  
-Dr. [[Anthony Fauci]] speaks on the clinical trial for potential coronavirus treatment drug remdesivir;+Dr. [[:Anthony Fauci]] speaks on the clinical trial for potential coronavirus treatment drug remdesivir;
  
 “What it has proven is that a drug can block this virus ... This drug happens to be blocking an enzyme that the virus uses." ((https://twitter.com/NBCNews/status/1255541788154224641?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug))((https://web.archive.org/web/20220216133756/https://twitter.com/NBCNews/status/1255541788154224641?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug))((https://web.archive.org/web/20220216140546/https://twitter.com/PeterHotez/status/1312355823889330178?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug)) “What it has proven is that a drug can block this virus ... This drug happens to be blocking an enzyme that the virus uses." ((https://twitter.com/NBCNews/status/1255541788154224641?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug))((https://web.archive.org/web/20220216133756/https://twitter.com/NBCNews/status/1255541788154224641?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug))((https://web.archive.org/web/20220216140546/https://twitter.com/PeterHotez/status/1312355823889330178?s=20&t=Bp5Prr6eeVTMe-tHn7b5Ug))
  
-As a side note, besides Fauci, a cast of characters well known among those who have been investigating the lab leak hypothesis make their appearance. [[Peter Daszak]] was sure to claim credit for assisting in the development of remdesivir. (60 minutes) ((https://twitter.com/60Minutes/status/1260278403908931588))+As a side note, besides Fauci, a cast of characters well known among those who have been investigating the lab leak hypothesis make their appearance. [[:Peter Daszak]] was sure to claim credit for assisting in the development of remdesivir. (60 minutes) ((https://twitter.com/60Minutes/status/1260278403908931588))
 "The breakthrough drug Remdesivir that seems to have some impact on COVID-19, was actually tested against the viruses we discovered under our NIH research," says disesase ecologist Peter Daszak, whose coronavirus research grant was just cut by the NIH" ((https://web.archive.org/web/20220116000225/https://twitter.com/60Minutes/status/1260278403908931588 | 60 Minutes Interview)) "The breakthrough drug Remdesivir that seems to have some impact on COVID-19, was actually tested against the viruses we discovered under our NIH research," says disesase ecologist Peter Daszak, whose coronavirus research grant was just cut by the NIH" ((https://web.archive.org/web/20220116000225/https://twitter.com/60Minutes/status/1260278403908931588 | 60 Minutes Interview))
  
-But the real hero in the development of remdesivir is Mr. Gain-of-function himself, [[Ralph Baric]]. What was his role? Allow him to explain..+But the real hero in the development of remdesivir is Mr. Gain-of-function himself, [[:Ralph Baric]]. What was his role? Allow him to explain..
  
 "It's a game changer," says Dr. Ralph Baric, an epidemiologist about data that suggests the experimental drug remdesivir might help patients recover more quickly from the infection. "It's a game changer," says Dr. Ralph Baric, an epidemiologist about data that suggests the experimental drug remdesivir might help patients recover more quickly from the infection.
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