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--- covid-19:treatments:drug_therapies:hydroxychloroquine [2022/01/05 08:22]
kalev [Links to be Sorted]
+++ covid-19:treatments:drug_therapies:hydroxychloroquine [2022/10/05 01:02] (current)
mathew
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 ==== Prior Research ====
 Since shortly after the first [[:SARS-CoV]] outbreak, researchers compiled evidence that chloroquine and hydroxychloroquine would likely help fight another deadly [[:coronavirus]] outbreak.((Mar 25, 2021 | [[:Rounding The Earth]] | [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-vii|Why Did Dr. Anthony Fauci Leave Hydroxychloroquine Off the Early Pandemic Research Priority List?]]))
+  * In 2005, researcher Martin Vincent and colleagues noted that chloroquine is a potent inhibitor of SARS coronavirus infection and spread.((August 22, 2005 | Vincent et al | [[:Virology Journal]] | [[https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69|doi: 10.1186/1743-422X-2-69]]))
-==== Antiviral Properties Research ====
+==== Antiviral Properties Research (Mechanisms) ====
+  * Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture((September 14, 2022 | Zixuan Yuan et al | Nature (journal) | Hydroxychloroquine blocks SARS-CoV-2 entry into the endocytic pathway in mammalian cell culture | [[https://www.nature.com/articles/s42003-022-03841-8|doi.org/10.1038/s42003-022-03841-8]]))
 ===== Evidence for Prophylaxis =====