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sars-cov-2 [2022/04/07 09:29] mathew | sars-cov-2 [2022/09/19 04:39] (current) pamela | ||
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====== SARS-CoV-2 ====== | ====== SARS-CoV-2 ====== | ||
- | {{ :: | + | {{ :: |
**SARS-CoV-2** is a humanborne [[coronavirus]] in the // | **SARS-CoV-2** is a humanborne [[coronavirus]] in the // | ||
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The SARS-CoV-2 virus is a close genetic relative of two other infamous viruses from recent history: [[SARS-CoV-1|SARS-CoV]] and [[MERS-CoV]].((Rabaan, | The SARS-CoV-2 virus is a close genetic relative of two other infamous viruses from recent history: [[SARS-CoV-1|SARS-CoV]] and [[MERS-CoV]].((Rabaan, | ||
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+ | {{ :: | ||
Related Pages: | Related Pages: | ||
* [[SARS-CoV-2: | * [[SARS-CoV-2: | ||
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* [[SARS-CoV-2: | * [[SARS-CoV-2: | ||
* [[SARS-CoV-2: | * [[SARS-CoV-2: | ||
- | + | * [[COVID-19]] | |
+ | * [[COVID-19 Pandemic]] | ||
+ | * [[COVID-19 Vaccines]] | ||
+ | threadreader for inage ((https:// | ||
===== SARS-CoV-2 Viral Mechanisms and Characteristics ===== | ===== SARS-CoV-2 Viral Mechanisms and Characteristics ===== | ||
SARS-CoV-2 is a positively charged, single-stranded [[RNA virus]]. | SARS-CoV-2 is a positively charged, single-stranded [[RNA virus]]. | ||
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==== Pathology ==== | ==== Pathology ==== | ||
* Dec, 2020 - Liao et al; SARS-CoV-2 in the bile of a patient with COVID-19-associated gallbladder disease.((December, | * Dec, 2020 - Liao et al; SARS-CoV-2 in the bile of a patient with COVID-19-associated gallbladder disease.((December, | ||
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+ | Researchers have found in autopsies that SARS-CoV-2 does get into brain tissue, and can be present for months after infection, though inflammation outside of the lungs was mild.((December 20, 2021 | Daniel Chertow et al | Nature Portfolio (journal) | SARS-CoV-2 infection and persistence throughout the human body and brain | [[https:// | ||
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+ | See [[SARS-CoV-2: | ||
==== Transmission and Infectivity ==== | ==== Transmission and Infectivity ==== | ||
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== Infectivity in Animal Hosts == | == Infectivity in Animal Hosts == | ||
+ | [[https:// | ||
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Numerous animals aside from humans have been noted to be susceptible to SARS-CoV-2 infection. Comparative and structural analysis on 410 vertebrate species predicts a broad host range for infection, specifically among mammals.((September 8, 2020 | Damas et al | [[: | Numerous animals aside from humans have been noted to be susceptible to SARS-CoV-2 infection. Comparative and structural analysis on 410 vertebrate species predicts a broad host range for infection, specifically among mammals.((September 8, 2020 | Damas et al | [[: | ||
One study still in preprint found SARS-CoV-2 moving rapidly into white-tailed deer populations in North America, with over 80% of the deer testing PCR positive for the virus by early 2021.((November 6, 2021 | Kuchipudi et al | preprint | [[https:// | One study still in preprint found SARS-CoV-2 moving rapidly into white-tailed deer populations in North America, with over 80% of the deer testing PCR positive for the virus by early 2021.((November 6, 2021 | Kuchipudi et al | preprint | [[https:// | ||
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=== Reinfections === | === Reinfections === | ||
+ | During the early part of the COVID-19 pandemic, physicians and scientists found that reinfections were extremely rare.((May 19, 2020 | ScienceNews.org | [[https:// | ||
+ | |||
During the omicron era, reinfections are rapidly on the rise.((March 21, 2022 | [[:Igor Chudov]] | [[https:// | During the omicron era, reinfections are rapidly on the rise.((March 21, 2022 | [[:Igor Chudov]] | [[https:// | ||
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+ | === Transference of Immunity === | ||
+ | Scientists have noted evidence for aerosol transfer of SARS-CoV-2-specific humoral immunity.((May 1, 2022 | Kedl et al | preprint | Evidence for Aerosol Transfer of SARS-CoV2-specific Humoral Immunity | [[https:// | ||
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==== COVID-19 ==== | ==== COVID-19 ==== | ||
- | SARS-CoV-2 is a cause of [[COVID-19]], | + | SARS-CoV-2 is a cause of [[COVID-19]], |
==== Genetic and Epigenetic Effects of Infection ==== | ==== Genetic and Epigenetic Effects of Infection ==== | ||
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See more at [[SARS-CoV-2: | See more at [[SARS-CoV-2: | ||
+ | ===== Controversies ===== | ||
- | ===== SARS-CoV-2 Origins Story Controversy | + | ==== SARS-CoV-2 Origins Story Controversy ==== |
The [[SARS-CoV-2: | The [[SARS-CoV-2: | ||
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+ | ==== Retracted Research ==== | ||
+ | Many papers have been retracted during the [[COVID-19 pandemic]]. Here are some that relate specifically to SARS-CoV-2, though others may be found at [[Retraction Watch]]. | ||
+ | * SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro((October 13, 2021 | Jiang and Mei | Viruses (journal) | SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro | [[https:// |