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Helen Rees

Helen Rees is a South African medical researcher based in Johannesburg, South Africa.

Education

Rees attended the University of Cambridge as a medical student where she was an organizer for the group ‘Medicine in Society’, which “aimed to introduce topical social issues as part of a broader learning experience for medical undergraduates.” She received a Master’s Degree in Women’s Studies.

After completing her early medical training in London, she and her husband moved to Zimbabwe. She spent two years working at Harare Hospital as a registrar in pediatrics and neonatal medicine.

Career and Affiliations

Wits Reproductive Health and HIV Institute (1994-present)

Rees is the founder and executive director of the Wits Reproductive Health and HIV Institute (RHI) at the University of the Witwatersrand.1)

African Leadership in Vaccinology Excellence

Rees is a co-founder and co-director of African Leadership in Vaccinology Excellence (ALIVE), the flagship vaccinology programme at the University of the Witwatersrand.2)

London School of Hygiene and Tropical Medicine

Rees is an Honorary Professor in the Department of Clinical Research at the London School of Hygiene and Tropical Medicine.3)

South Africa National Advisory Group on Immunization

World Health Organization

Rees plays a leadership role in several World Health Organization expert committees and initiatives:

  • Chair of the International Health Regulations Review Committee on Polio5)
  • Former chair of WHO's Strategic Advisory Group of Experts (SAGE) on Immunization6)
  • STI Vaccine Roadmap Committee7)
  • WHO African Regional Immunization Technical Advisory Group8)
  • WHO Committee Developing Regulations to Cover Clinical Trials and Research During Emergencies9)
  • WHO Ebola Vaccine Working Group10)
  • WHO Expert Committee on HPV Vaccines11)
  • WHO HIV Vaccine Expert Committee12)

GE2P2 Global Foundation

Rees delivered a keynote presentation at the 2011 Global Vaccines 202X Access, Equity, Ethics Symposium titled WHO’s Immunization Policy Framework: Is it achieving its goal?13) She was introduced to the audience by Paul Offit. The symposium was hosted by the Center for Vaccine Ethics and Policy (CVEP), a program of the GE2P2 Global Foundation.14) Rees is a fellow of the foundation.15)

The GE2P2 Global Foundation is supported by the Alliance for Regenerative Medicine, a consortium of gene therapy pharmaceutical companies including Astellas, Bristol-Myers Squibb, CRISPR Therapeutics, CSL, Fresenius Kabi, GE Healthcare, Gilead Sciences (through Kite Pharma), GlaxoSmithKline, Johnson & Johnson, Novartis, Novo Nordisk, Oxford Biomedica, Pfizer, Sanofi, Spark Therapeutics, Takeda, Terumo, and Thermo Fisher Scientific.16)

Gavi, the Vaccine Alliance

Rees is a member of the board of directors for Gavi, the Vaccine Alliance.17)

Population Council

Rees serves as a technical expert for the Population Council.18)

South African Health Products Regulatory Authority (SAHPRA)

Rees is chair of the South African Health Products Regulatory Authority (SAHPRA) Board.19) SAHPRA is the organization in charge of regulating the use of all health products throughout South Africa, including COVID-19 vaccines.20) Rees oversaw the approval of the injections from Pfizer, Johnson & Johnson, and AstraZeneca.

National Institute of Communicable Diseases

Rees is a member of the Scientific Advisory Committee at the National Institute of Communicable Diseases.

Coalition for Epidemic Preparedness Innovations

Rees is Chair of the Scientific Advisory Board of the Coalition for Epidemic Preparedness Innovations (CEPI).21)

International AIDS Vaccine Initiative

Rees is a member of the Board of the International AIDS Vaccine Initiative (IAVI).22)

Sabin-Aspen Vaccine Science & Policy Group

Rees is a member of the Sabin-Aspen Vaccine Science & Policy Group, an initiative of the Sabin Vaccine Institute and the Aspen Institute.23) The group is funded by the Bill & Melinda Gates Foundation and Wellcome Trust.

Ministerial Advisory Committee on COVID-19 and Vaccines

COVID-19 Clinical Research Coalition

Research

SOLIDARITY Trial (2020-2022)

Rees is the Co-Chair of the South African arm of the SOLIDARITY Trial, the World Health Organization-sponsored study on repurposed drugs for use as COVID-19 treatments.33) 34) The drugs under examination included hydroxychloroquine, remdesivir, and “antiviral drugs commonly used for HIV.”35)

CROWN CORONATION Study (2020-2022)

Rees is a Principal Investigator for the COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION (CROWN CORONATION) study, investigating strategies to protect healthcare workers against COVID-19 infection.36) The study is sponsored by the COVID-19 Therapeutics Accelerator, a funding initiative paid for by the Bill & Melinda Gates Foundation, Mastercard, Wellcome Trust,37) 38) the Government of the United Kingdom, Madonna, and the Chan Zuckerberg Initiative,39) as well as pharmaceutical companies BD, Boehringer Ingelheim, bioMerieux, Eisai, Eli Lilly, Gilead Sciences, GlaxoSmithKline, Johnson & Johnson, Merck (both the US and German divisions), Novartis, Pfizer, and Sanofi.40)

Additional Funding

1)
Professor Helen Rees, Executive Director. (2022). Wits RHI. https://archive.ph/rEX2I
2)
Consortium Members. (2022). Wits-Alive. https://archive.ph/Up8kq
3)
Prof Helen Rees. The Presidency. Retrieved June 3, 2022, from https://archive.ph/YuwxO
4)
Helen Rees, MD, MA, MRCGP | AME. (2022). Academic Medical Eduction. https://archive.ph/YbD6m
5)
Biographies of the members of, and advisers to, the IHR Emergency Committee concerning ongoing events and context involving transmission and international spread of poliovirus. World Health Organization. Retrieved June 4, 2022, from https://web.archive.org/web/20211123101026/https://cdn.who.int/media/docs/default-source/documents/ihr/ihr-committee-members-polio.pdf?sfvrsn=b174ea_2
6)
What is SAGE? (2011, October 21). Wayback Machine; World Health Organization. https://web.archive.org/web/20141018235933/http://www.who.int/immunization/newsroom/multimedia/helen_rees/en/
7)
Gottlieb, S. L., Deal, C. D., Giersing, B., Rees, H., Bolan, G., Johnston, C., Timms, P., Gray-Owen, S. D., Jerse, A. E., Cameron, C. E., Moorthy, V. S., Kiarie, J., & Broutet, N. (2016). The global roadmap for advancing development of vaccines against sexually transmitted infections: Update and next steps. Vaccine, 34(26), 2939–2947. https://doi.org/10.1016/j.vaccine.2016.03.111
8)
GPEI-Q&A with Helen Rees. (2020, August 25). Global Polio Eradication Initiative. https://archive.ph/Qk5OZ
9)
Helen Rees - Founder, Director, Professor of Obstetrics and Gynecology in Johannesburg, Gauteng, South Africa. (2022). EMedEvents. https://www.emedevents.com/speaker-profile/helen-rees
10)
Jasarevic, T. (2019, May 7). WHO adapts Ebola vaccination strategy in the Democratic Republic of the Congo to account for insecurity and community feedback. World Health Organizatioon. https://www.who.int/news/item/07-05-2019-who-adapts-ebola-vaccination-strategy-in-the-democratic-republic-of-the-congo-to-account-for-insecurity-and-community-feedback
11)
Strategic Advisory Group of Experts (SAGE) Working Group on potential contribution of HPV vaccines and immunization towards cervical cancer elimination (established June 2018). (2021, November 24). World Health Organization. https://archive.ph/AdEAT
12)
Professor Helen Rees. (2015). Events Cloud. https://archive.ph/dwitN
13)
Curry, D. R. (2011, May 16). Symposium – Global Vaccines 202X: Access, Equity, Ethics. Center for Vaccine Ethics and Policy. https://archive.ph/zgDxl
14)
Curry, D. R. (2009, March 2). About us. Center for Vaccine Ethics and Policy. https://centerforvaccineethicsandpolicy.net/about/
15)
Helen Rees, MD, OBE. (2019, February 19). GE2P2 Global Foundation. https://archive.ph/MEZpD
16)
Advancing Gene, Cell, & Tissue-Based Therapies. Alliance for Regenerative Medicine. Retrieved June 3, 2022, from https://alliancerm.org/sector-report/2019-annual-report
17)
Helen Rees. (2022). Gavi, the Vaccine Alliance. https://archive.ph/JJMKz
18)
Professor Helen Rees. (2016, May 25). Murray Edwards College - University of Cambridge. https://archive.ph/1hjWJ
19)
The SAHPRA Board. (2022). SAHPRA. https://archive.ph/G7xmz
20)
SAHPRA update on Vaccine Approvals. (2021, June 21). SAHPRA. https://archive.ph/krWIz
21)
Gutierrez, Jr., O. R. (2020, June 29). Partnership science. POZ. https://archive.ph/mKx1V
22)
Professor Helen Rees (Chairperson). (2013, October 7). World Health Organization. https://web.archive.org/web/20200909093333/https://www.who.int/immunization/sage/members/bio_rees/en/
23)
The Group. The Sabin-Aspen Vaccine Science & Policy Group. Retrieved June 5, 2022, from https://archive.ph/WqVzI
24)
Ministerial Advisory Committees on COVID-19 (pp. 4, 8). (2020). Bhekisisa Centre for Health Journalism. https://web.archive.org/web/20220303122616/https://bhekisisa.org/wp-content/uploads/2020/05/38bf41e2-ministerial-advisory-committees-on-covid-19.pdf
25)
SABC News. (2021, August 22). Focus on the COVID-19 vaccines with Professor Helen Rees. YouTube. https://web.archive.org/web/20220603233806/https://www.youtube.com/watch?v=T9pJL_u6wog
26)
Witz RHI. (2022, March 9). French National Order of Merit awarded to Professor Helen Rees - Wits University. University of the Witwatersrand, Johannesburg. https://archive.ph/nQTlU
27)
Helen Rees. COVID-19 Clinical Research Coalition. Retrieved June 3, 2022, from https://archive.ph/pBgkH
28)
Donors. COVID-19 Clinical Research Coalition. Retrieved June 3, 2022, from https://archive.ph/OAJwb
29)
Industry partners and service providers. DNDi. Retrieved June 3, 2022, from https://archive.ph/28sJH
30)
Universities and Research Centres. DNDi. Retrieved June 3, 2022, from https://archive.ph/Jsnj9
31)
Non-profit Organizations and Networks. DNDi. Retrieved June 3, 2022, from https://archive.ph/EY0c1
32)
Ministries of Health and Governments. DNDi. Retrieved June 3, 2022, from https://archive.ph/9wUBu
33)
WHO Solidarity Trial Consortium. (2020). Repurposed antiviral drugs for COVID-19 — Interim WHO Solidarity Trial results. New England Journal of Medicine. https://doi.org/10.1056/nejmoa2023184
34)
#ListenToTheExperts Prof Helen Rees, Exec Director, Wits RHI tells us about the Solidarity Trial. (2020, May 18). SA Corona Virus Online Portal. https://sacoronavirus.co.za/2020/05/18/listentotheexperts-prof-helen-rees-exec-director-wits-rhi-tells-us-about-the-solidarity-trial/
35)
WHO Solidarity Trial Consortium. (2022). Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(22)00519-0
36)
Avidan, M., Washington University School of Medicine, & COVID-19 Therapeutics Accelerator. (2022, January 27). An international, multi-site, Bayesian platform adaptive, randomized, placebo-controlled trial assessing the effectiveness of candidate agents in mitigating COVID-19 disease in adults. ClinicalTrials.gov. https://archive.ph/Ploh3
37)
COVID-19 Therapeutics Accelerator. (2020, March 10). Bill & Melinda Gates Foundation. https://archive.ph/uXOjt
38)
Suzman, M. (2020, March 10). Announcing the COVID-19 Therapeutics Accelerator. Bill & Melinda Gates Foundation. https://archive.ph/Z8Q5l
39)
Au-Yeung, A. (2020, April 3). A Bill Gates-backed accelerator for COVID-19 therapeutics treatment partners with Madonna and Mark Zuckerberg’s Chan Zuckerberg Initiative. Forbes. https://archive.ph/WGnvO
40)
Staines, R. (2020, March 26). Pharma giants including Novartis collaborate on COVID-19 therapies. Pharmaphorum; Pharmaphorum Media Limited. https://archive.ph/8TAzM
41)
Rees, H. Multipurpose Prevention Technologies: New drugs, New Delivery Systems. South African HIV Clinicians Society. Retrieved June 5, 2022, from https://sahivsoc.org/Files/Fri_Helen_Rees%20Co-formulation%20HIV%20prevention%20and%20contraception.pdf
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