====== Zhengli Shi ====== ===== History ===== ==== Education ==== Shi earned her masters degree from the [[Wuhan Institute of Virology]] in 1990. Later, she earned her PhD in [[France]] at the [[Montpellier 2 University]] while becoming fluent in French. ==== Career ==== === Director of Wuhan Institute of Virology === ==== Coronavirus Research ==== === 2005 === In the wake of the 2002-2003 SARS-CoV outbreak, Shi and collegues found that bats are a natural reservoir of SARS-like CoVs.((october 31, 2005 | Li Wendong et al including Shi Zhengli and [[Peter Daszak]] | [[Science (journal)]] | Bats Are Natural Reservoirs of SARS-Like Coronaviruses | [[https://zenodo.org/record/3949088|https://doi.org/10.1126/science.1118391]])) === 2013 === In 2013, researchers at the Wuhan Institute of Virology published a paper saying that Dr. Zhengli Shi and [[EcoHealth Alliance]]'s Dr. [[Peter Daszak]] found CoVs that were 95% identical to human SARS-CoV in Chinese [[horseshoe bats]]. Further, these CoVs "were able to use human angiotensin-converting enzyme 2 ([[ACE2]]) receptor for docking and entry."((December, 2013 | Manli Wang and Zhihong Hu | Virol Sin. (journal) | Bats as animal reservoirs for the SARS coronavirus: Hypothesis proved after 10 years of virus hunting | [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091109/|doi: 10.1007/s12250-013-3402-x]])) === 2020 === In March 2020, Shi and co-authors published a paper asserting that [[Remdesivir]] and [[chloroquine]] worked as therapeutics against [[SARS-CoV-2]].((Wang, M., Cao, R., Zhang, L., Yang, X., Liu, J., Xu, M., Shi, Z., Hu, Z., Zhong, W., & Xiao, G. (2020). //Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.// Cell Research, 30(3), 269–271. https://doi.org/10.1038/s41422-020-0282-0)) ===== External links ===== * [[https://sites.google.com/housatonicits.com/home0005/research/zheng-li-shi-b1964|Houstaonic]] * [[https://en.wikipedia.org/wiki/Shi_Zhengli|Wikipedia]]