====== Rounding The Earth: The Chloroquine Wars ====== The following articles appear as part of [[:Rounding the Earth]]'s **The Chloroquine Wars** series. However, some articles originally in that series now best fit in other series indexes, so appear elsewhere in the wikified RTE hierarchy. ===== Early Treatment Medications ===== ==== The Chloroquines ==== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-i|Drugs of the Cinchona Tree]] A history of medicines derived from the [[:Cinchona]] tree, originally of [[:South America]], such as [[:quinine]], [[:chloroquine]] (CQ), [[:hydroxychloroquine]] (HCQ), and others. This includes historical evidence of [[:antiviral]] properties. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-viii|Hydroxychloroquine's Safety Profile and a Cost-Benefit Analysis]] Since [[:hydroxychloroquine]] (HCQ) is extremely inexpensive, and relatively safe with almost no serious adverse reactions under physician observation, HCQ has a positive risk-benefit if any one protocol has a modestly positive effect in the prevention or treatment of COVID-19. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-v|A Closer Look at RCTs Studying Hydroxychloroquine Efficacy]] Reviews the [[:randomized control trials]] (RCTs) studying HCQ efficacy in treating COVID-19 patients, showing tremendously positive results. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-vi|The Simple Logic of the Hydroxychloroquine Hypothesis]] explains why evidence against the efficacy of a suboptimal protocol is not evidence against the efficacy of a drug or other medical agent. * **The primary question**: Is hydroxychloroquine (HCQ) effective in fighting SARS-CoV-2 and the associated COVID-19 condition? * **The Hydroxychloroquine Hypothesis**: That there is some appropriate dosage of hydroxychloroquine, alone or in some combination with other medication, that successfully prevents some COVID-19 cases (PrEP/PEP) or treats some COVID-19 sufferers (Early/Late/Critical). * [[https://roundingtheearth.substack.com/publish/post/34353305|Why Did Dr. Anthony Fauci Leave Hydroxychloroquine Off the Early Pandemic Research Priority List?]] Details how numerous research papers declared chloroquine and hydroxychloroquine the most likely drugs to help handle a [[:coronavirus]] outbreak. Dr. [[:Anthony Fauci]] and his coauthors were entirely alone among coronavirus and infectious disease experts in not looking first to these medications. * [[https://roundingtheearth.substack.com/p/how-to-rig-research-the-who-edition|How to Rig Research: The WHO Edition]] * [[https://roundingtheearth.substack.com/p/how-to-rig-research-the-who-edition-105|How to Rig Research: The WHO Edition Part II]] === Doctors Using Hydroxychloroquine === * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xxv|https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xxv]] ==== Ivermectin, Too ==== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xxi|Dr. Pierre Kory Eviscerates the Case Against Ivermectin]] * [[https://roundingtheearth.substack.com/p/journal-editors-resign-over-suppression|Journal Editors Resign Over Suppression of Ivermectin Research Paper]] ===== Propaganda ===== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-ii|The Curious Calm Before the Storm]] * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-vii|Why Did Dr. Anthony Fauci Leave Hydroxychloroquine Off the Early Pandemic Research Priority List?]] * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-ix|How to Rig Research by Statistically Stacking the Deck (A Simpson's Paradox Tale)]] How evidence of efficacy, such as that of hydroxychloroquine's efficacy, gets covered up through the mixing of pools of patients treated under different protocols. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xii|Manufactured Fear During Hydroxychloroquine's Trump Moment]] Evidence of artificially engineered propaganda timed with Trump's March 19, 2020 press conference mentioning hydroxychloroquine. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xiii|A Clockwork Orange Man]] The arrangement of Trump and Fauci as players in a large scale [[Asch conformity experiment]]. * [[https://roundingtheearth.substack.com/p/institutional-funding-of-propaganda|Institutional Funding of Propaganda Against Early Treatment of COVID-19]] * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xvii|Why the Story About India's April COVID-19 Spike is All Wrong]] India's "spike" says more about the efficacy of early treatment than it is a panic story. * [[https://roundingtheearth.substack.com/p/what-if-the-sars-cov-2-virus-is-weaker|What if the SARS-CoV-2 Virus is Weaker Than Most Everyone Thinks?]] ===== Medical Trials and Statistics ===== ==== RCT Fundamentalism ==== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-iii|A Critique of RCTs: The Gold Standard is Neither Supreme nor Ultimate]] explains why [[:randomized control trials]] (RCTs) should not be viewed as the ultimate standard of medical evidence. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-iv|A Critique of RCTs: Historical Failure to Strike Gold]] reviews literature demonstrating that RCTs tend to show the same results as observational evidence of medical effects. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-v|A Closer Look at RCTs Studying Hydroxychloroquine Efficacy]] Reviews the [[:randomized control trials]] (RCTs) studying HCQ efficacy in treating COVID-19 patients, showing tremendously positive results. ==== How to Rig Research ==== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-ix|How to Rig Research by Statistically Stacking the Deck (A Simpson's Paradox Tale)]] How evidence of efficacy, such as that of hydroxychloroquine's efficacy, gets covered up through the mixing of pools of patients treated under different protocols. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xiv|How to Rig Research: Surgisphere, Part 1]] The story of prominent story of research fraud that was used to manipulate national and international public health policy and perception. * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xv|How to Rig Research: Surgisphere, Part 2]] * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xx|Why The Early Treatment Data is Better Than Anyone Imagines: Dr. Brian Tyson's Data]] * [[https://roundingtheearth.substack.com/p/how-to-rig-research-the-who-edition|How to Rig Research: The WHO Edition]] * [[https://roundingtheearth.substack.com/p/how-to-rig-research-the-who-edition-105|How to Rig Research: The WHO Edition Part II]] ===== Historical Failures of Public Health ===== * [[https://roundingtheearth.substack.com/p/historical-failures-of-public-health|Historical Failures of Public Health Authorities]] * [[https://roundingtheearth.substack.com/p/pandemos-is-this-what-sanity-looks-531|Pandemos -- Is This What Sanity Looks Like?]] =====Interviews ===== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-x|A Discussion of the Insanity of the Chloroquine Wars]] **(Now censored from [[:YouTube]])** ===== Plandemonium ===== * [[https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xi|See No Good, Hear No Good, Speak No Good]] Authorities are clearly overlooking simple solutions in favor of authoritarian ones. * [[https://roundingtheearth.substack.com/p/what-does-the-absurd-tell-us-about|What Does the Absurd Tell us About the Pandemic?]] See also [[Rounding the Earth:The Plandemonium]]