====== Quercetin ======
**Quercetin** is an [[antioxidant]] with substantial free radical scavenging activities.

===== Antiviral Properties =====
Quercetin has been noted to be a [[zinc ionophore]].

https://pubmed.ncbi.nlm.nih.gov/25050823/,

==== Efficacy in Prevention and Treatment of SARS-CoV-2/COVID-19 ====
During the [[SARS-CoV-2/COVID-19 pandemic]], [[quercetin]] studies indicate likely substantial efficacy in the prevention of [[SARS-CoV-2]] infection and treatment of [[COVID-19]].

https://c19quercetin.com/

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7356916/

https://www.sciencedirect.com/science/article/pii/S0968089606007310?via%3Dihub

https://www.preprints.org/manuscript/202003.0226/v1

https://journals.asm.org/doi/10.1128/jvi.78.20.11334-11339.2004?permanently=true

=== Clinical Trials ===

A clinical trial application for "isoquercetin" was submitted to [[Health Canada]] by [[Pharmascience Inc.]] in partnership with [[Montreal Clinical Research Institute]] (MCRI)/Institut de Recherches Cliniques de Montréal (IRCM), and the [[International Consortium on Anti-Virals]] (ICAV) on May 30, 2020. The group described isoquercetin as "a wide spectrum anti-viral" with potential to treat patients hospitalized with mild to moderate COVID-19. In partnership with the [[National Microbiology Laboratory]] in Winnipeg, Manitoba, the group had already demonstrated that "isoquercetin is effective against the [[Ebola]] and [[Zika]] viruses in animals and against the SARS CoV-2 (sic) virus //in vitro//." Further, the authors note that the compound is naturally-occurring and is present in most people's diets (such as in onions).((//Isoquercetin Clinical Trial Application Submitted to Health Canada.// (2020, May 30). ICAV. https://icav-citav.com/icav_news/isoquercetin-clinical-trial-application-submitted-to-health-canada/))

This trial was approved on or around July 17, 2020. Capsules containing a patented Isoquercetin formulation called ISQ950AN were supplied by [[Quercis Pharma AG]] out of Switzerland.((//Health Canada approves isoquercetin COVID-19 trial - ICAV network 2nd trial.// (2020, July 19). ICAV. https://icav-citav.com/icav_news/health-canada-approves-isoquercetin-clinical-trial-second-covid-19-trial-from-the-icav-network/))