====== Drug Therapies Researched or Applied to Treat COVID-19 ======
From early on during the [[:COVID-19 pandemic]], many potential drug therapies became and remain controversial. The various medications in this article may include both effective and ineffective treatments of the [[:SARS-CoV-2]] virus and the resulting [[:COVID-19]] disease state. The primary purpose is to categorize and summarize those treatments here.

===== How to Procure SARS-CoV-2/COVID-19 Prophylaxis and Treatments =====
See [[COVID-19:How to Procure Medicine for COVID-19]]

===== Research Summaries =====
Hundreds of studies on dozens of drugs used during the COVID-19 pandemic are documented and summaried at [[https://c19early.com/|www.c19study.com]].

====Antiseptic Mouth/Nose Wash ====
  * [[COVID-19:treatments:Povidone-Iodine]]
  * [[COVID-19:treatments:Chlorhexidine]]
  * [[COVID-19:treatments:Cetylpyridinium Chloride]]
  * [[COVID-19:treatments:Chlorhexidine Gluconate]]
  * [[COVID-19:treatments:Iota-Carrageenan]]

===== Antidepressants =====
While [[:antidepressants]] may not seem like the most important class of repurposed drugs, COVID-19 is a unique disease, and it may not always be clear what biochemical influences might help some of those affected fight off the disease.
  * [[COVID-19:treatments:drug_therapies:fluvoxamine]]

===== Antivirals =====
An [[:antiviral]] agent is any agent that works as an antiviral, and may or may not otherwise be ordinarily recognized as a [[:drug]] or have other medical uses.
  * [[COVID-19:treatments:drug_therapies:amodiaquine]]
  * [[COVID-19:treatments:drug_therapies:chloroquine]]
  * [[COVID-19:treatments:drug_therapies:curcumin]]
  * [[COVID-19:treatments:drug_therapies:hydroxychloroquine]]
  * [[COVID-19:treatments:drug_therapies:favipiravir]]
  * [[COVID-19:treatments:drug_therapies:ivermectin]]
  * [[COVID-19:treatments:drug_therapies:lithium]]
  * [[COVID-19:treatments:drug_therapies:molnupiravir]]
  * [[COVID-19:treatments:drug_therapies:niclosamide]]
  * [[COVID-19:treatments:drug_therapies:nitazoxanide]]
  * [[COVID-19:treatments:drug_therapies:PAXLOVID™]]]
  * [[COVID-19:treatments:drug_therapies:quercetin]]
  * [[COVID-19:treatments:drug_therapies:remdesivir]]

See also [[COVID-19:treatments:drug_therapies:zinc ionophores]]

=====Anti-Androgen Therapy ======
  * [[COVID-19:treatments:Spironolactone]]
  * [[COVID-19:treatments:Dutasteride]]
  * [[COVID-19:treatments:Finasteride]]
  * [[COVID-19:treatments:Proxalutamide]]

===== Blood Thinners/Anticoagulants =====
Since clotting is among the most damaging symptoms of COVID-19, numerous [[:anticoagulants]] have been used by some doctors.

===== Fusion Inhibitor Peptides =====

==== Enfuvirtide ====
An in silico study showed that enfuvirtide can act as a potent [[:SARS-CoV-2]] fusion inhibitor.((September 11, 2020 | Khadijeh Ahmadi et al | Enfuvirtide, an HIV-1 fusion inhibitor peptide, can act as a potent SARS-CoV-2 fusion inhibitor: an in silico drug repurposing study | [[https://www.tandfonline.com/doi/full/10.1080/07391102.2021.1871958|https://doi.org/10.1080/07391102.2021.1871958]]))

=====Immune Modulators =====
  * [[COVID-19:treatments:Dexamethasone]]
  * [[COVID-19:treatments:Budesonide (inhaled)]]
  * [[COVID-19:treatments:Azithromycin]]
  * [[COVID-19:treatments:Interferons]]
  * [[COVID-19:treatments:Monoclonal Antibodies]]

===== Oxygen =====

==== Ventilators ====

===== Steroids =====

==== Corticosteroids ====

====Other Mechanisms of Action ====
  * [[COVID-19:treatments:Melatonin]]
  * [[COVID-19:treatments:Colchicine]]
  * [[COVID-19:treatments:Statins]]
  * [[COVID-19:treatments:Aspirin]]
  * [[COVID-19:treatments:Famotidine]]

==== Public Health Measures ====
See [[List of SARS-CoV-2 pandemic public health measures]]


==== Vaccines ====
Many [[COVID-19 vaccines]] have been deployed with others in the development pipeline.


==== Vitamins, Minerals, and Nutraceuticals ====
Many vitamins, minerals, and nutraceutical supplements have been proposed, tested, or used in the treatment of SARS-CoV-2 and COVID-19.

   * [[Vitamin C]]
   * [[Vitamin D3]]
   * [[Zinc]]
   * [[Quercetin]]
   * [[NAC]]
   * [[Nigella Sativa]]
   * [[Curcumin]]
   * [[Probiotics]]
   * [[Vitamin A]]
   * [[Epigallocatechin-gallate (EGCG)]]
   * [[Lactoferrin]]

==== Multidrug Treatment Protocols ====
Many medical doctors have shared the results of multidrug treatment protocols that they have used with patients in their practice. 

^ Protocol Name ^ # of patients treated ^ # of patients hospitalized ^ # of patients died ^ Case Fatality Rate ^
| Dr. Syed Haider IVM + FLV((https://drsyedhaider.com/covid-19/my-experience-flccc-treatment-and-prevention-protocols)) |  4,000+  |  5  |  0  |  0  |
| Zelenko High Risk Patient Protocol ((https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587171/))|  141  |  4  |  1   |  0.7%  |
| Tyson Farid mild|   7,000   |  2  |  0  |  0  |
| Tyson Farid moderate((https://roundingtheearth.substack.com/p/the-chloroquine-wars-part-xx))|   413   |  7  |  3  |  0.7%  | 
| Italy Protocol |  66,000  |  ?  |  4  |  0.00606%  |
| Chetty 8th Day Therapy ((https://www.deccanchronicle.com/lifestyle/health-and-wellbeing/310521/is-covid-19-treatment-based-on-trial-and-error.html)) ((https://www.youtube.com/watch?v=OciYTW_BIEs))|  4,000  |
| Demello ((https://odysee.com/@DrMobeenSyed:1/dr.-darrell-demello-discusses-covid-3:1))|   10,000+   |   ??   |   ??   |   ??   |  

Dr. Peter McCullough has also developed early outpatient treatment protocols, publishing his findings at the end of 2020 and beginning of 2021:
https://pubmed.ncbi.nlm.nih.gov/33387997/
https://pubmed.ncbi.nlm.nih.gov/32771461/