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--- pharmaceutical_companies:moderna [2022/08/17 03:17]
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+++ pharmaceutical_companies:moderna [2024/05/01 18:33] (current)
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 ====== Moderna ======
-{{ :pharmaceutical_companies:modernalogo.png?200|}}
+{{ :pharmaceutical_companies:moderna_logo_.png?200|}}
 **Moderna, Inc.** is an American [[:pharmaceutical_companies|pharmaceutical]] and [[:biotechnology]] company based in [[:united_states_of_america:massachusetts:Cambridge]], [[:united_states_of_America:Massachusetts]].
+===== History =====
+Moderna began collaborating with [[alexion|Alexion Pharmaceuticals]] in January 2014, entering an agreement for ten product options based on Moderna's mRNA platform.((//Elpidera.// (2016). Moderna Therapeutics. https://archive.ph/uennQ)) ((Reidy, C. (2014, January 13). //Alexion, Moderna announce agreement to develop messenger RNA therapeutics.// Boston Globe Media Partners. https://web.archive.org/web/20230605072835/https://www.boston.com/news/innovation/2014/01/13/alexion-moderna-announce-agreement-to-develop-messenger-rna-therapeutics/)) On January 14, 2014, Moderna announced the creation of [[Onkaido Therapeutics]] to focus "exclusively on developing mRNA-based [[:oncology]] treatments."((Favorito, M. (2014, January 14). //Moderna Launches Onkaido Therapeutics to Focus on the Development of mRNA TherapeuticsTM in Oncology with $20 Million Capital Commitment.// Moderna Therapeutics. http://archive.today/2016.11.20-035524/http://www.modernatx.com/news-events/press-releases/moderna-launches-onkaido-therapeutics-focus-development-mrna-therapeuticstm)) ((Gormley, B. (2014, January 15). //Moderna Launches Cancer Drug Co. Onkaido Therapeutics With $20M Investment.// Wall Street Journal. http://archive.today/2023.06.05-073743/https://www.wsj.com/amp/articles/DJFVW00020140114ea1eqwhzn))
+On January 8, 2015, Moderna announced the launch of its second spinoff company, Valera, "focused exclusively on the advancement of vaccines and therapeutics for the prevention and treatment of viral, bacterial and parasitic infectious diseases."[5]
+On May 12, 2015, Moderna announced the launch of its third spinoff company, Elpidera, intended to "advance novel messenger RNA therapies" while continuing Moderna's work with Alexion.[6]
+On October 22, 2015, Moderna announced the launch of its fourth spinoff company, [[Caperna]], intended to "focus exclusively on the advancement of personalized [[:cancer vaccines]]."((Melone, L. (2015, October 22). //Moderna Launches Caperna LLC, Its Fourth Venture, to Develop Personalized Cancer Vaccines.// Moderna Therapeutics. https://web.archive.org/web/20161119220026/http://www.modernatx.com/news-events/press-releases/moderna-launches-caperna-llc-its-fourth-venture-develop-personalized-cancer)) Caperna's work involved collaborations with [[Merck]].((//Caperna LLC.// (2016). Moderna Therapeutics. https://web.archive.org/web/20161029183424/http://www.modernatx.com/our-business-model/ventures/caperna-llc))
+On January 12, 2016, Moderna announced that it had entered a funding agreement with the [[:Bill & Melinda Gates Foundation]] to develop therapeutics against [[:HIV]] and other diseases. The agreement included an initial $20 million grant, with the potential to increase the amount to $100 million.((//Bill & Melinda Gates Foundation — Advancing an mRNA-based antibody combination to help prevent HIV infection.// Moderna. Retrieved March 21, 2022, from http://archive.today/2021.08.23-023928/https://www.modernatx.com/ecosystem/strategic-collaborators/foundations-advancing-mrna-science-and-research)) ((//Moderna Wins Initial $20M Grant from Gates Foundation.// (2016, January 12). GEN - Genetic Engineering and Biotechnology News. http://archive.today/2023.02.03-040340/https://www.genengnews.com/topics/omics/moderna-wins-initial-20m-grant-from-gates-foundation/))
 ===== Organization =====
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 In addition to its core business, Moderna spun out several venture firms to focus on different applications of their [[:mRNA]] delivery technology.
-  * [[Elpidera]]
+  * [[Caperna]] focused exclusively on the advancement of personalized [[:cancer vaccines]].((//Caperna LLC.// (2016). Moderna Therapeutics. https://web.archive.org/web/20161029183424/http://www.modernatx.com/our-business-model/ventures/caperna-llc))
+  * [[Elpidera]] was formed to develop mRNA-based medicines to treat rare diseases.((//Elpidera.// (2016). Moderna Therapeutics. https://archive.ph/uennQ))
   * [[Onkaido Therapeutics]] was focused exclusively on the advancement of [[:oncology]] products for previously "undruggable" targets.((//mRNA-based Oncology Treatments.// Onkaido Therapeutics. Retrieved October 12, 2016, from https://web.archive.org/web/20161012181337/http://onkaido.com/about/))
   * [[Valera]] was formed to focus exclusively on the development of [[:vaccines]] and therapeutics for the prevention and treatment of [[:virus|viral]], [[:bacteria|bacterial]] and [[:parasite|parasitic]] [[:infectious diseases]].((//Valera.// (2016). Moderna Therapeutics. https://archive.ph/erYpO))
@@ Line 112: / Line 125: @@
 Just kidding. They never produced a product before inventing the very first functional [[:mRNA vaccine]] is approximately 53 hours, 13 minutes and 47 seconds.
-=== Moderna's mRNA-1273 Injectable Product ===
+==== Moderna's mRNA-1273 Injectable Product ====
+Moderna's groundbreaking [[:Moderna mRNA-1273]] coronavirus vaccine was designed in just 2 days. ((https://www.campfire.wiki/doku.php?id=moderna_mrna-1273))
 == Production of mRNA-1273 ==
@@ Line 132: / Line 147: @@
 ==== Stephane Bancel ====
-In February, 2022, Bancel deleted his Twitter account.((February 12, 2022 | Justin Hart (Tweet) | [[https://twitter.com/justin_hart/status/1492595091529109506?t=pgMxk_WjqhChWR0Hp_WIaA&s=03|https://twitter.com/justin_hart/status/1492595091529109506?t=pgMxk_WjqhChWR0Hp_WIaA&s=03]]))
+In February, 2022, [[:Stephane Bancel]] deleted his Twitter account.((February 12, 2022 | Justin Hart (Tweet) | [[https://twitter.com/justin_hart/status/1492595091529109506?t=pgMxk_WjqhChWR0Hp_WIaA&s=03|https://twitter.com/justin_hart/status/1492595091529109506?t=pgMxk_WjqhChWR0Hp_WIaA&s=03]]))
 ==== HIV Vaccine ====
@@ Line 139: / Line 154: @@
 st Century Wire News Desk - February 11, 2022
-In the past few days the topic of HIV/AIDS has been thrust back into the spotlight. On 27 January, it was announced that Moderna is launching clinical trials for a new [[HIV vaccine]] using [[:mRNA technology]]. A few days later on 3 February, Oxford University researchers published a study in the [[:Journal Science]] claiming discovery of the “[[VB variant]]” of HIV, and describing it as “highly virulent”.
+In the past few days the topic of HIV/AIDS has been thrust back into the spotlight. On 27 January, it was announced that Moderna is launching clinical trials for a new [[HIV vaccine]] using [[:mRNA technology]]. A few days later on 3 February, [[:Oxford University]] researchers published a study in the [[:Journal Science]] claiming discovery of the “[[VB variant]]” of HIV, and describing it as “highly virulent”.
 This news about the VB variant’s higher virulence was a point that mainstream news media made sure to repeat and amplify. Here are a selection of headlines covering the story:
@@ Line 177: / Line 192: @@
 The biotech giant said retired CFO David Meline would return to the role until Moderna can identify a permanent replacement. “The announcement follows the May 10 public disclosure by Mr. Gomez’s former employer, Dentsply Sirona Inc., of an ongoing internal investigation into certain matters, including financial reporting,” Moderna said, without providing further details on the matter. ((https://web.archive.org/web/20220511161539/https://nypost.com/2022/05/11/moderna-cfo-jorge-gomez-exits-after-one-day-on-the-job/))
+==== Company Linked to CIA Now Making mRNA for Moderna’s Reformulated COVID Booster Shots ====
+Since late last year, messenger RNA for Moderna’s COVID-19 vaccines, including its recently reformulated Omicron booster, has been exclusively manufactured by [[:National Resilience]], a little-known company with significant ties to US intelligence.
+By  Whitney Webb
+However, unlike the company’s original COVID-19 vaccine, the genetic material, or messenger RNA (mRNA), for this new vaccine, including the newly formulated genetic material meant to provide protection against the Omicron variant, is being manufactured, not by Moderna, but by a relatively new company that has received hardly any media attention, despite its overt links to U.S. intelligence.
+Last September, it was quietly announced that a company called National Resilience (often referred to simply as Resilience) would begin manufacturing the mRNA for Moderna COVID-19 vaccine products.
+Under the terms of the multi-year agreement, “Resilience will produce mRNA for the Moderna COVID-19 vaccine at its facility in Mississauga, Ontario, for distribution worldwide.” ((https://web.archive.org/web/20220823213925/https://childrenshealthdefense.org/defender/cia-linked-mrna-moderna-omicron-covid-booster-shot/?utm_source=salsa&eType=EmailBlastContent&eId=b11817f6-0f42-4571-a4d1-685bcf5b4005))
+==== US Open Sponsor 2022 ====
+{{ :pharmaceutical_companies:moderna_2022_winston_salem_dimitrov.png?800|}}
+Reuters - Tennis: Top seed Dimitrov forced to retire against Thiem in Winston-Salem
+With less than a week to go before the start of the [[:US Open]], the 31-year-old Bulgarian came out sharp, unleashing a torrent of backhanded slices to keep Thiem off balance as he raced through the surprisingly one-sided first set 6-0.
+But things took a turn for the worse for world No. 19 Dimitrov at 2-2 in the second and he began to misfire in bunches in an apparent attempt to shorten points. fter a visit from medical staff, he stepped up to the line to serve while trailing 2-4 but decided he was feeling too unwell to continue and shook hands at the net, where he waited for Thiem while hunched over. ((https://web.archive.org/web/20220824090653/https://www.straitstimes.com/sport/tennis/tennis-top-seed-dimitrov-forced-to-retire-against-thiem-in-winston-salem))
+{{:pharmaceutical_companies:moderna_sponsor_us_open.png?800|}}
+===== External links =====
+  * [[https://wiki.whiteroseintelligence.com/en/Moderna|White Rose Wiki]]
+  * [[https://wikispooks.com/wiki/Moderna|Wikispooks]]