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covid-19_vaccines:adverse_events [2022/01/23 16:20]
mathew Nocebo effect		covid-19_vaccines:adverse_events [2022/08/21 07:14] (current)
mathew
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 ====== Adverse Events Following COVID-19 Vaccination ====== ====== Adverse Events Following COVID-19 Vaccination ======
-[[COVID-19 Vaccine]] [[adverse events]] is a challenging topic because they are so numerous and of broad variety.+[[:COVID-19 Vaccines|COVID-19 Vaccine]] [[adverse events]] is a challenging topic because they are so numerous and of broad variety.
  
 Research shows that the treatment arm of Covid 19 vaccine trials had significantly more adverse events than the placebo arm.((https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788172)) [[https://www.campfire.wiki/doku.php?id=covid-19_vaccines:adverse_event_reporting_databases|Several databases]] are tracking adverse events resulting from the widespread public roll out of these vaccines. Research shows that the treatment arm of Covid 19 vaccine trials had significantly more adverse events than the placebo arm.((https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788172)) [[https://www.campfire.wiki/doku.php?id=covid-19_vaccines:adverse_event_reporting_databases|Several databases]] are tracking adverse events resulting from the widespread public roll out of these vaccines.
 +
 +===== Adverse Events Following COVID-19 Vaccination (by ICD-10 Organization) =====
 +  * G00-G99;H00-H95: [[covid-19_vaccines:adverse_events:Nervous System and Sense Organs]]
 +  * L00-L99: [[covid-19_vaccines:adverse_events:Skin and Subcutaneous Tissue]]
 +
 +===== COVID-19 Vaccine Associated Auto-Immune Disorders =====
 +
 +==== Lupus ====
 +  * New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination((February 11, 2022 | Baez-Negron and Vila | Case Reports in Rheumatology | New-Onset Systemic Lupus Erythematosus after mRNA SARS-CoV-2 Vaccination | [[https://www.hindawi.com/journals/crirh/2022/6436839/|https://doi.org/10.1155/2022/6436839]]))
  
 ===== COVID-19 Vaccine Associated Cardiac Injuries ===== ===== COVID-19 Vaccine Associated Cardiac Injuries =====
 +  * Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave((April 28, 2022 | Sun et al | Nature (journal) | Increased emergency cardiovascular events among under-40 population in Israel during vaccine rollout and third COVID-19 wave | [[https://www.nature.com/articles/s41598-022-10928-z|https://doi.org/10.1038/s41598-022-10928-z]]))
  
 ==== Myocarditis ==== ==== Myocarditis ====
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   * [[https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab707/6353927|Aug 18, 2021| Li et al]] Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model   * [[https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab707/6353927|Aug 18, 2021| Li et al]] Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model
  
-===== COVID-19 Vaccine Associated Neurological Events ===== 
- 
-==== Guillain-Barré Syndrome ==== 
- 
-See also: [[covid-19_vaccines:adverse_events:guillain-barré|CoVid-19 Vaccine Associated Guillain-Barré]] 
- 
-Guillain-Barré is a neurological disorder in which the body's immune system mistakenly attacks part of its peripheral nervous system—the network of nerves located outside of the brain and spinal cord. GBS can range from a very mild case with brief weakness to nearly devastating paralysis, leaving the person unable to breathe independently. Fortunately, most people eventually recover from even the most severe cases of GBS. After recovery, some people will continue to have some degree of weakness. 
- 
-==== Bell’s Palsy, Facial Paralysis & Facial Palsy ==== 
- 
-See also:  [[covid-19_vaccines:adverse_events:bell’s_palsy|CoVid-19 Vaccine Associated Facial and Bell’s Palsy]] 
- 
-==== Myelitis, including Transverse Myelitis  ==== 
- 
-See also:  [[covid-19_vaccines:adverse_events:myelitis|CoVid-19 Vaccine Associated Myelitis, including Transverse Myelitis]] 
- 
-==== Generalized Neurological Complications ==== 
- 
-See also:  [[covid-19_vaccines:adverse_events:generalized_CNS_events|CoVid-19 Vaccine Associated Generalized Neurological Complications]] 
- 
-==== Unexplained Cases ==== 
- 
-From 2020-2021, a localized epidemic of sudden neurological diseases have appeared affecting patients from their 20s to their 80s in the [[Province of New Brunswick]], Canada. "If a group of people wanted to breed conspiracy theorists, then our government has done a wonderful job at promoting it,” said Tim Beatty, son of one victim. “Are they just trying to create a narrative for the public that they hope we’ll absorb and walk away from? I just don’t understand it.”((Cecco, L. (2022, January 2). //Whistleblower warns baffling illness affects growing number of young adults in Canadian province.// The Guardian. https://archive.ph/4DcSO)) It is unclear what the cause of the epidemic is, and the New Brunswick government appears to be trying to suppress a deeper investigation. 
  
 ===== COVID-19 Vaccine Associated Blood and Vascular Disorders ===== ===== COVID-19 Vaccine Associated Blood and Vascular Disorders =====
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 ===== COVID-19 Vaccine Associated Fertility-Related AEs ===== ===== COVID-19 Vaccine Associated Fertility-Related AEs =====
 +
 ===== COVID-19 Vaccine Associated Disorders of the Immune System ===== ===== COVID-19 Vaccine Associated Disorders of the Immune System =====
  
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 See also:  [[covid-19_vaccines:adverse_events:lymphadenopathy:immune_mediated_disease|CoVid-19 Vaccine Associated Immune-mediated Disease]] See also:  [[covid-19_vaccines:adverse_events:lymphadenopathy:immune_mediated_disease|CoVid-19 Vaccine Associated Immune-mediated Disease]]
 +
  
 ===== COVID-19 Vaccine Associated Inflammation ===== ===== COVID-19 Vaccine Associated Inflammation =====
  
-===== COVID-19 Vaccine Associated Hepatitis ===== 
  
-==== Immune-mediated Hepatitis ====+===== COVID-19 Vaccine Associated Infectious Disease ===== 
 + 
 +==== Herpes Zoster ==== 
 +In a study published in late 2021, researchers found reactivation of [[:herpes zoster]] among 1.2% of patients receiving BNT162b2 mRNA injections among those with autoimmune inflammatory rheumatic diseases (AIIRD), but none among the 99 patients without AIIRD.((October 9, 2021 | Victoria Furer et al | [[:Rheumatology]] (Oxford) | Herpes zoster following BNT162b2 mRNA COVID-19 vaccination in patients with autoimmune inflammatory rheumatic diseases: a case series | [[https://pubmed.ncbi.nlm.nih.gov/33848321/|DOI: 10.1093/rheumatology/keab345]])) The control group may be too small for a good comparison. 
 + 
 +==== Hepatitis ==== 
 + 
 +=== Immune-mediated Hepatitis ===
  
 See also: [[covid-19_vaccines:adverse_events:hepatitis|Covid-19 Vaccine Associated Hepatitis]] See also: [[covid-19_vaccines:adverse_events:hepatitis|Covid-19 Vaccine Associated Hepatitis]]
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 https://www.ahajournals.org/doi/abs/10.1161/circ.144.suppl_1.10712 https://www.ahajournals.org/doi/abs/10.1161/circ.144.suppl_1.10712
  
-===== COVID-19 Vaccine Associated Previously Rare Diseases =====+==== COVID-19 Vaccine Associated Previously Rare Diseases ====
  
 ===Eosinophilic Granulomatosis with Polyangiitis=== ===Eosinophilic Granulomatosis with Polyangiitis===
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 [[https://academic.oup.com/qjmed/advance-article/doi/10.1093/qjmed/hcab273/6413650#316486976|Eosinophilic granulomatosis with polyangiitis (EGPA) has been associated with CoVid Vaccination]].  EGPA (formerly Churg-Strauss Syndrome) is an extremely rare disease caused by inflammation of blood and/or tissue cells, which previously was known to effect only two to five new people a year per one million people. [[https://nypost.com/2021/12/27/trailer-park-boys-star-candy-palmater-dies-suddenly-at-53/|Candy Palater, star of Trailer Park Boys, died]] after being hospitalized and diagnosed with eosinophilic granulomatosis with polyangiitis. [[https://academic.oup.com/qjmed/advance-article/doi/10.1093/qjmed/hcab273/6413650#316486976|Eosinophilic granulomatosis with polyangiitis (EGPA) has been associated with CoVid Vaccination]].  EGPA (formerly Churg-Strauss Syndrome) is an extremely rare disease caused by inflammation of blood and/or tissue cells, which previously was known to effect only two to five new people a year per one million people. [[https://nypost.com/2021/12/27/trailer-park-boys-star-candy-palmater-dies-suddenly-at-53/|Candy Palater, star of Trailer Park Boys, died]] after being hospitalized and diagnosed with eosinophilic granulomatosis with polyangiitis.
  
-===== In the Previously Infected =====+===== COVID-19 Vaccine Associated Neurodegenerative Disease ===== 
 +Sixteen cases of [[:Creutzfeldt-Jakob]] disease were reported by researches among those who received COVID-19 vaccination.((February, 2022 | Claire Moret-Chalmin et al | preprint | Towards the emergence of a new form of the neurodegenerative Creutzfeldt-Jakob disease: Sixteen cases of CJD declared a few days after a COVID-19 “vaccine” Jab | [[https://www.researchgate.net/publication/358661859_Towards_the_emergence_of_a_new_form_of_the_neurodegenerative_Creutzfeldt-Jakob_disease_Sixteen_cases_of_CJD_declared_a_few_days_after_a_COVID-19_vaccine_Jab|DOI:10.13140/RG.2.2.14427.03366]])) 
 + 
 +===== AEs Among the Previously Infected =====
  
 Numerous studies show significantly higher rates of adverse events amongst those who previously had COVID-19 infections. Numerous studies show significantly higher rates of adverse events amongst those who previously had COVID-19 infections.
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 ===== Quantification of COVID-19 Vaccine Associated Adverse Events ===== ===== Quantification of COVID-19 Vaccine Associated Adverse Events =====
 +German physician, Dr. Erich Freisleben, estimates severe adverse events at 3% based on his clinical volume.((April 3, 2022 | No Tricks Zone | [[https://notrickszone.com/2022/04/03/berlin-physician-estimates-cases-of-severe-side-effects-at-3-projected-one-million-affected-in-germany/|Berlin Physician Estimates Cases Of Severe Side Effects At 3%…Projected One Million Affected In Germany]]))
  
 ==== AE Reporting Databases ==== ==== AE Reporting Databases ====
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 ==== The Nocebo Hypothesis ==== ==== The Nocebo Hypothesis ====
 In an meta-analysis published by the [[:Journal of the American Medical Association]], researchers suggested that a substantial portion of COVID-19 vaccine associated AEs are the result of the [[:nocebo]] effect.((January 18, 2022 | Julia Haas et al | [[:Journal of the American Medical Association]] Network Open | [[https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788172|doi:10.1001/jamanetworkopen.2021.43955]]))  In an meta-analysis published by the [[:Journal of the American Medical Association]], researchers suggested that a substantial portion of COVID-19 vaccine associated AEs are the result of the [[:nocebo]] effect.((January 18, 2022 | Julia Haas et al | [[:Journal of the American Medical Association]] Network Open | [[https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788172|doi:10.1001/jamanetworkopen.2021.43955]])) 
 +  * Fundamentally, this suggests that those who volunteered as test subjects for vaccine research were people with expectations that the vaccines would harm them. If true, the implications about the relationship between [[:pharmaceutical corporations]] and their patients is profoundly disturbing. It also suggests a lack of agency among those participating in vaccine testing experiments. None of this is taken into account by the researchers.
   * The meta-analysis failed to analyze the effect of unblinding of the vaccine trials.   * The meta-analysis failed to analyze the effect of unblinding of the vaccine trials.
   * The meta-analysis failed to observe the large proportion of suspected, but untested and undiagnosed cases of COVID-19 in some of the studies.   * The meta-analysis failed to observe the large proportion of suspected, but untested and undiagnosed cases of COVID-19 in some of the studies.
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