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covid-19_vaccines:adverse_events:myocarditis [2022/01/27 17:50]
brian [Research]
covid-19_vaccines:adverse_events:myocarditis [2022/07/15 06:21] (current)
liam
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 ====== COVID-19 Vaccine Associated Myocarditis ====== ====== COVID-19 Vaccine Associated Myocarditis ======
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 During the experimental [[:COVID-19 vaccines]] campaign, many vaccine recipients have suffered vaccine-associated [[:myocarditis]]. There is a debate over the nature of the damage caused in these cases of myocarditis as well as the relative risk of myocarditis associated with [[:SARS-CoV-2]] infection or [[:COVID-19]] cases. During the experimental [[:COVID-19 vaccines]] campaign, many vaccine recipients have suffered vaccine-associated [[:myocarditis]]. There is a debate over the nature of the damage caused in these cases of myocarditis as well as the relative risk of myocarditis associated with [[:SARS-CoV-2]] infection or [[:COVID-19]] cases.
  
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 ===== Research ===== ===== Research =====
 +
 Increased occurrence of myocarditis, pericarditis and myopericarditis has been associated with Covid-19 inoculations,((https://www.nature.com/articles/s41591-021-01630-0)) along with Covid-19 infection.  Increased occurrence of myocarditis, pericarditis and myopericarditis has been associated with Covid-19 inoculations,((https://www.nature.com/articles/s41591-021-01630-0)) along with Covid-19 infection. 
  
 {{ :myocarditis_vaers.jpg?600 |}} {{ :myocarditis_vaers.jpg?600 |}}
  
- +^             Incidence of Myocarditis Following the Second Dose of a Covid-19 mRNA Vaccine               ^^^^^^^^^  
-^             Incidence of Myocarditis Following the Second Dose of a Covid-19 mRNA Vaccine                ^^^^^^^^  +^  ^  Male: Age 12-15  ^  Male: Age 12-17  ^   Male: Age 16-17    Male: Age 16-19    Male: Age 18-24  ^  Male: Age < 30  ^  Male: Age < 40  ^  Rate from Sars-cov-2  ^
-^  ^  Male: Age 12-15  ^  Male: Age 12-17  ^   Male: Age 16-17  ^   Male: Age 18-24  ^  Male: Age < 30  ^  Male: Age < 40  ^  Rate from Sars-cov-2  ^+
 | Kaiser Permanente Study - Dec 27, 2021((https://www.medrxiv.org/content/10.1101/2021.12.21.21268209v1))|  -  |  1 / 1860    1 / 2650    |   | Kaiser Permanente Study - Dec 27, 2021((https://www.medrxiv.org/content/10.1101/2021.12.21.21268209v1))|  -  |  1 / 1860    1 / 2650    |  
 | Nature Medicine Paper - Dec 25, 2021((https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1))|  -  |    -  |  101 excess events per million (Moderna)  |   30 excess events per million  | | Nature Medicine Paper - Dec 25, 2021((https://www.medrxiv.org/content/10.1101/2021.12.23.21268276v1))|  -  |    -  |  101 excess events per million (Moderna)  |   30 excess events per million  |
 | USA FDA ACIP Meeting Presentation((http://dx.doi.org/10.15585/mmwr.mm7027e2)) |  |    62.8 per million  |    50.5 per million  | | USA FDA ACIP Meeting Presentation((http://dx.doi.org/10.15585/mmwr.mm7027e2)) |  |    62.8 per million  |    50.5 per million  |
 | Israel MoH((https://www.nejm.org/doi/full/10.1056/NEJMc2116999?query=featured_home)) |  1 / 12,361   | | Israel MoH((https://www.nejm.org/doi/full/10.1056/NEJMc2116999?query=featured_home)) |  1 / 12,361   |
-| Oster, CDC((https://jamanetwork.com/journals/jama/fullarticle/2788346)) |  71 per million (pfizer)  |  106 per million (pfizer)  |    |   56 per million (moderna)  |+| Oster, CDC((https://jamanetwork.com/journals/jama/fullarticle/2788346)) |  71 per million (pfizer)  |  106 per million (pfizer)  |    |   |   56 per million (moderna)  | 
 +| Mevorach, Israel((https://www.nejm.org/doi/full/10.1056/NEJMoa2109730)) |  -  |    |  -  |   1 / 6637  | 
 + 
 +A research letter published by JAMA claimed that rates of myocarditis and pericarditis increased less than 100% post-vaccination.((August 4, 2021 | George A. Diaz et al | [[:JAMA]] | Myocarditis and Pericarditis After Vaccination for COVID-19 | [[https://jamanetwork.com/journals/jama/fullarticle/2782900|doi:10.1001/jama.2021.13443]])) 
  
 ==== CDC Reports ==== ==== CDC Reports ====
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 The CDC continued to recommend use of these vaccinations while urging doctors to follow a list of clinical guidelines and to make VAERS reports as needed. ((https://www.cdc.gov/vaccines/covid-19/clinical-considerations/myocarditis.html)) The CDC continued to recommend use of these vaccinations while urging doctors to follow a list of clinical guidelines and to make VAERS reports as needed. ((https://www.cdc.gov/vaccines/covid-19/clinical-considerations/myocarditis.html))
  
-In the December 31, 2020 MMWR the CDC released information related to COVID-19 vaccine safety in children aged 5–11 years, covering the November 3–December 19, 2021 period of slightly over a five weeks.  The information was drawn from VEARS and VSAFE and was restricted to those who received Pfizer-BioNTech COVID-19 vaccine. ((https://www.cdc.gov/mmwr/volumes/70/wr/mm705152a1.htm))+In the December 31, 2021 MMWR the CDC released information related to COVID-19 vaccine safety in children aged 5–11 years, covering the November 3–December 19, 2021 period of slightly over a five weeks.  The information was drawn from VEARS and VSAFE and was restricted to those who received Pfizer-BioNTech COVID-19 vaccine. ((https://www.cdc.gov/mmwr/volumes/70/wr/mm705152a1.htm))
  
 ==== Small Hong Kong Studies ==== ==== Small Hong Kong Studies ====
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 [[https://www.nejm.org/doi/full/10.1056/NEJMc2116999?query=featured_home|Myocarditis after BNT162b2 Vaccination in Israeli Adolescents]] [[https://www.nejm.org/doi/full/10.1056/NEJMc2116999?query=featured_home|Myocarditis after BNT162b2 Vaccination in Israeli Adolescents]]
 +
 +[[https://pubmed.ncbi.nlm.nih.gov/35404496/|Risk of myopericarditis following COVID-19 mRNA vaccination in a large integrated health system: A comparison of completeness and timeliness of two methods]]
  
 ===== Link dump ===== ===== Link dump =====
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