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--- covid-19_vaccine_risk:prion_disease [2021/12/17 06:46]
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-====== COVID-19 Associated Prion Disease ======
-===== Research =====
-  * Aug 18, 2014, Olsthoorn ([[https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4132711/|paper]]) in Nucleic Acids Research: G-quadruplexes within prion mRNA: the missing link in prion disease?
-  * * This is extremely relevant to the [[mRNA vaccine]]s, because the [[codon]] optimization that they do to greatly increase the amount of spike protein cells produce also ends up increasing the number of potential [[G-quadruplex]]es that the [[mRNA]] can form. The combination of more spike protein and more availability of G-quadruplexes would be devastating for the potential to cause prion diseases.