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pamela [SARS-CoV2 Antibody B Cells]
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 Several distinct B-cell subsets have been defined that possess distinct functions in both adaptive and innate humoral immune responses. ((https://web.archive.org/web/20181225064152/https://www.immunology.org/public-information/bitesized-immunology/cells/b-cells))
+==== SARS-CoV2 Antibody B Cells ====
+Broad Institute - April 27, 2021 - By Sarah C.P. Williams
+A study of antibody-producing B cells from patients who recovered from [[:COVID-19]] reveals a new cross-reactive antibody and what makes some B cells more effective at neutralizing the virus.
+Inside the body of a person with COVID-19, the immune system’s B cells are engaged in a full-scale battle with the SARS-CoV-2 virus. But some B cells are better at this than others. Now, scientists from the Broad Institute of [[:MIT]] and [[:Harvard]], [[:Massachusetts General Hospital]], [[:California Institute of Technology]], [[:Brigham and Women’s Hospital]], and other institutions have for the first time described key characteristics of B cells that are effective at neutralizing, or inactivating, the SARS-CoV-2 virus and related coronaviruses.
+The team studied blood samples from 14 people who recovered from COVID-19, and revealed distinct patterns of gene expression in B cells that produce antibodies that bind tightly to and neutralize SARS-CoV-2. They also discovered a **new antibody, BG10-19, which neutralizes the virus**, variants of concern such as ones first identified in the UK and South Africa, and the coronavirus that caused the 2003 SARS outbreak.
+The findings, published today in Cell, could help scientists better understand why some people don’t respond as well to existing COVID-19 vaccines or therapies, a first step toward improving vaccines and treatments. ((https://www.broadinstitute.org/news/how-b-cells-fight-covid-19-virus))